Ziegler W, Loscher B
Strahlentherapie. 1985 Oct;161(10):636-41.
During combined treatment of hamster kidney cells with cisplatin and irradiation under aerobic conditions, there appear interactions between the two treatment modalities. The presence of cisplatin during irradiation leads to an increased bending, pretreatment or posttreatment with cisplatin to a gradual adaption of the shape of the survival curve to a straight line. Simultaneous treatment of hamster kidney cells with cisplatin and irradiation in hypoxia does not change the survival curve in contrast to simultaneous treatment under aerobic conditions.
在需氧条件下，用顺铂和辐射联合处理仓鼠肾细胞时，两种处理方式之间会出现相互作用。辐射期间顺铂的存在会导致弯曲增加，顺铂预处理或后处理会使存活曲线形状逐渐适应直线。与需氧条件下的同时处理相反，在缺氧条件下用顺铂和辐射同时处理仓鼠肾细胞不会改变存活曲线。
