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原发性头痛中睡眠、焦虑和情绪障碍管理的实际问题

Practical issues in the management of sleep, anxiety, and mood disorders in primary headaches.

作者信息

Sousa-Santos Patrick Emanuell Mesquita, Peres Mario Fernando Prieto

机构信息

Universidade Estadual Paulista, Botucatu SP, Brazil.

Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Instituto de Psiquiatria, São Paulo SP, Brazil.

出版信息

Arq Neuropsiquiatr. 2025 Jul;83(7):1-8. doi: 10.1055/s-0045-1809881. Epub 2025 Jul 2.

DOI:10.1055/s-0045-1809881
PMID:40602800
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12221693/
Abstract

There are many conditions associated with primary headaches, including mood (depression), anxiety, and sleep disorders, which are highly prevalent in the general population and in tertiary headache centers. We call this set of symptoms migraine, anxiety, mood, and sleep (MAMS). The presence of one or more of these symptoms can alter the clinical course and represent a practical challenge. In the present study, we aimed to describe a practical approach to treat these symptoms frequently associated with headaches. Diagnostic aspects and secondary causes were addressed as well as the shared mechanisms and cause and effect relationship. Finally, we commented on the therapeutic approach used to treat these symptoms.

摘要

有许多与原发性头痛相关的情况,包括情绪(抑郁)、焦虑和睡眠障碍,这些在普通人群和三级头痛中心都非常普遍。我们将这组症状称为偏头痛、焦虑、情绪和睡眠(MAMS)。这些症状中出现一种或多种会改变临床病程并带来实际挑战。在本研究中,我们旨在描述一种治疗这些经常与头痛相关症状的实用方法。还探讨了诊断方面和继发原因以及共同机制和因果关系。最后,我们对用于治疗这些症状所采用的治疗方法进行了评论。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30a1/12221693/a377898290b2/10-1055-s-0045-1809881-i240318-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30a1/12221693/a7b1e11bc593/10-1055-s-0045-1809881-i240318-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30a1/12221693/a377898290b2/10-1055-s-0045-1809881-i240318-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30a1/12221693/a7b1e11bc593/10-1055-s-0045-1809881-i240318-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30a1/12221693/a377898290b2/10-1055-s-0045-1809881-i240318-2.jpg

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本文引用的文献

1
The history and rationale of the development of new drugs for migraine treatment.偏头痛治疗新药的发展历程及原理。
Arq Neuropsiquiatr. 2023 Dec;81(12):1084-1097. doi: 10.1055/s-0043-1777723. Epub 2023 Dec 29.
2
Prevalence of depression and its correlation with anxiety, headache and sleep disorders among medical staff in the Hainan Province of China.中国海南省医务人员抑郁的患病率及其与焦虑、头痛和睡眠障碍的相关性。
Front Public Health. 2023 Jun 27;11:1122626. doi: 10.3389/fpubh.2023.1122626. eCollection 2023.
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Serotonin and dopamine transporter availability in social anxiety disorder after combined treatment with escitalopram and cognitive-behavioral therapy.
社交焦虑障碍患者在接受艾司西酞普兰联合认知行为治疗后,其 5-羟色胺和多巴胺转运体的可利用性。
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Erenumab Impact on Sleep Assessed With Questionnaires and Home-Polysomnography in Patients With Migraine: The ERESON Study.依瑞卡单抗对偏头痛患者睡眠的影响:通过问卷调查和家庭多导睡眠图评估——依瑞森研究
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CGRP Inhibitors and Oxidative Stress Biomarkers in Resistant Migraine: A Real-Life Study with Erenumab, Fremanezumab, and Galcanezumab.降钙素基因相关肽抑制剂与难治性偏头痛中的氧化应激生物标志物:一项关于erenumab、fremanezumab和galcanezumab的真实研究
J Clin Med. 2021 Oct 4;10(19):4586. doi: 10.3390/jcm10194586.
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Catastrophization is related to the patient and not to the severity of migraine.灾难化与患者有关,而与偏头痛的严重程度无关。
Arq Neuropsiquiatr. 2021 Aug;79(8):682-685. doi: 10.1590/0004-282X-anp-2020-0462.
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Comorbidities of primary headache disorders: a literature review with meta-analysis.原发性头痛障碍的共病:文献综述与荟萃分析。
J Headache Pain. 2021 Jul 14;22(1):71. doi: 10.1186/s10194-021-01281-z.
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Comorbid Bipolar Disorder and Migraine: From Mechanisms to Treatment.双相情感障碍与偏头痛共病:从机制到治疗
Front Psychiatry. 2021 Jan 11;11:560138. doi: 10.3389/fpsyt.2020.560138. eCollection 2020.
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Migraine and sleep disorders: a systematic review.偏头痛与睡眠障碍:系统性综述。
J Headache Pain. 2020 Oct 27;21(1):126. doi: 10.1186/s10194-020-01192-5.
10
Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.204 个国家和地区 1990-2019 年 369 种疾病和伤害导致的全球负担:2019 年全球疾病负担研究的系统分析。
Lancet. 2020 Oct 17;396(10258):1204-1222. doi: 10.1016/S0140-6736(20)30925-9.