Singhania Ashika, Borle Anjali, Godbole Surekha, Sathe Seema
Datta Meghe Institute of Higher Education and Research, Wardha, India.
, Wardha, India.
BMC Oral Health. 2025 Jul 2;25(1):983. doi: 10.1186/s12903-025-06253-2.
The use of photobiomodulation (PBM) therapy in implant dentistry for enhancing the osseointegration is proven in many studies. However, the cumulative data of its effect around dental implants in patients is limited.
The purpose of the present study was to evaluate the effect of the PBM therapy on primary and secondary implant stability.
The studies included in the review and meta-analysis were selected according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and the PICOS criteria. The RoB 2 tool was used for assessing the risk of bias and the RevMan software, v. 5.4, was used for meta-analysis. Quantitative analysis was done using two tools considering the implant stability measurement using Ostellmeter and radiographs as the outcome. The mean and standard deviation (M ± SD) values for implant stability as well as the sample size were extracted from the articles, and the inverse variance method with random effects was used for meta-analysis. The forest plots for all time intervals were inspected to estimate the heterogeneity.
A total of 117 articles were initially retrieved, out of which 62 remained after duplicate removal. 15 articles were included in the review for qualitative analysis and 8 were eligible for quantitative analysis. The meta-analysis showed that at 2 weeks, 4 weeks and 8 weeks, the control group showed better result than experimental group, at 3 weeks the implant stability favoured the experimental group whereas at 6 and 12 weeks there was no difference seen between control and experimental group.
The PBM therapy on implant stability has yielded mixed results. While some studies have demonstrated a positive effect, others have reported no significant impact. Consequently, further research is warranted to fully elucidate the effects of PBM therapy on implant stability.
许多研究已证实光生物调节（PBM）疗法在种植牙科中用于增强骨结合的有效性。然而，其在患者牙种植体周围效果的累积数据有限。
本研究旨在评估PBM疗法对种植体初期和二期稳定性的影响。
根据系统评价和Meta分析的首选报告项目（PRISMA）指南及PICOS标准，选择纳入本综述和Meta分析的研究。使用RoB 2工具评估偏倚风险，并使用RevMan 5.4软件进行Meta分析。采用两种工具进行定量分析，将使用Ostellometer测量种植体稳定性和X线片作为结果。从文章中提取种植体稳定性的均值和标准差（M±SD）值以及样本量，并采用随机效应的逆方差法进行Meta分析。检查所有时间间隔的森林图以评估异质性。
最初检索到117篇文章，去除重复后剩余62篇。15篇文章纳入综述进行定性分析，8篇符合定量分析条件。Meta分析显示，在2周、4周和8周时，对照组结果优于实验组；在3周时，种植体稳定性有利于实验组；而在6周和12周时，对照组和实验组之间无差异。
PBM疗法对种植体稳定性的结果不一。虽然一些研究显示出积极效果，但其他研究报告无显著影响。因此，有必要进一步研究以充分阐明PBM疗法对种植体稳定性的影响。
