Ellett Tyler R, Pippas Andrew, Rios Humberto, Willett William F, Diaz Maria B
Internal Medicine, St. Francis Emory Healthcare, Columbus, USA.
Hematology and Oncology, Piedmont Healthcare, Columbus, USA.
Cureus. 2025 Jul 1;17(7):e87097. doi: 10.7759/cureus.87097. eCollection 2025 Jul.
Poorly cohesive gastric adenocarcinoma is classified as a diffuse type of gastrointestinal tract tumor composed of undifferentiated cells with an inherent propensity for aggressive behavior. Recent trends in surveillance indicate that gastric cancer (GC) is affecting younger adults and is distinct from GC that occurs later in life. Early-onset gastric cancer (EOGC) is associated with various environmental and genetic factors. Younger patients with recurrent pyrosis may warrant earlier surveillance in light of this worrisome trend. Herein, we discuss a young male patient who developed non-hereditary, poorly cohesive gastric adenocarcinoma with an extended history of pyrosis despite long-term acid suppression and triple therapy for ().
低黏附性胃腺癌被归类为一种弥漫型胃肠道肿瘤，由具有侵袭性行为固有倾向的未分化细胞组成。近期的监测趋势表明，胃癌正在影响更年轻的成年人，且与老年期发生的胃癌有所不同。早发性胃癌（EOGC）与多种环境和遗传因素相关。鉴于这一令人担忧的趋势，有反复烧心症状的年轻患者可能需要更早进行监测。在此，我们讨论一名年轻男性患者，他患有非遗传性、低黏附性胃腺癌，尽管长期进行抑酸治疗和三联疗法治疗（），但仍有长期烧心病史。
