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针刺伤后肝炎病例血清中乙肝病毒DNA的测定

Determination of HBV DNA in serum in a case of needlestick hepatitis.

作者信息

Gmelin K, Theilmann L, Will H, Czygan P, Kommerell B

出版信息

Z Gastroenterol. 1985 Feb;23(2):60-3.

PMID:4060802
Abstract

HBV DNA in serum was determined by modified spot hybridization. A nurse of the dialysis staff was inoculated via needlestick with blood of a HBsAg-positive hemodialysis patient, who had 2000 pg HBV DNA per milliliter serum. After insufficient passive immunization the nurse developed transient anicteric hepatitis B. HBV DNA was positive in sera of the recipient before and at the beginning of the elevation of transaminases.

摘要

血清中的乙肝病毒DNA通过改良斑点杂交法测定。一名透析室工作人员的护士被一名乙肝表面抗原阳性的血液透析患者的血液针刺接种,该患者每毫升血清中有2000 pg乙肝病毒DNA。在被动免疫不足后,该护士发生了短暂的无黄疸型乙型肝炎。在转氨酶升高之前及开始升高时,受者的血清中乙肝病毒DNA呈阳性。

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