Büchler M, Malfertheiner P, Block S, Maier W, Beger H G
Z Gastroenterol. 1985 Feb;23(2):79-83.
Acute necrotizing pancreatitis according to the presented results leads to definite endo- and/or exocrine functional loss in 57% of the patients (n = 21, pancreatic necrosis ascertained by laparotomy) evaluated by orale glucose tolerance test, secretin-ceruletide-test and fluorescein-dilaurate-test. Morphological alterations developed in 76% of patients, predominantly cicatricial ductal lesions shown by ERCP. The finding of a normal pancreatic function after extended necrosis in 43% of the patients can be explained by the enormous functional reserve of the pancreatic gland.
根据所呈现的结果，通过口服葡萄糖耐量试验、促胰液素-蛙皮素试验和荧光素二月桂酸酯试验评估，急性坏死性胰腺炎会导致57%的患者（n = 21，通过剖腹术确定胰腺坏死）出现明确的内分泌和/或外分泌功能丧失。76%的患者出现形态学改变，主要是经内镜逆行胰胆管造影（ERCP）显示的瘢痕性导管病变。43%的患者在广泛坏死之后仍具有正常胰腺功能，这一发现可通过胰腺巨大的功能储备来解释。
