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胃旁路手术与袖状胃切除术的回顾性纵向比较观察研究:术后5年随访

Retrospective longitudinal and comparative observational study between gastric bypass surgery and sleeve gastrectomy: 5-year post-operative follow-up.

作者信息

Concon Filho Admar, Damous Sergio Henrique Bastos, Otoch Jose Pinhata, Coronado Matheus Borges, Zotarelli Filho Idiberto José, Galvão Neto Manoel Passos, Brunaldi Vítor Ottoboni, Artifon Everson Luiz Almeida

机构信息

Hospital e Maternidade Galileo, Surgery Unit - Valinhos (SP), Brazil.

Universidade de São Paulo, Faculty of Medicine, Department of Surgery - São Paulo (SP), Brazil.

出版信息

Arq Bras Cir Dig. 2025 Jun 27;38:e1885. doi: 10.1590/0102-67202025000016e1885. eCollection 2025.

Abstract

BACKGROUND

Among the 2.0 billion overweight individuals in the world, Brazil ranks fifth in the number of obese people, therefore requiring treatment options for obesity.

AIM

The aim of this study was to compare the percentage of total body weight loss (%TWL), change in body mass index (BMI), percentage of excess weight loss (%EWL), incidence of reflux esophagitis, and occurrence of Barrett's esophagus in obese patients undergoing gastric bypass (Roux-en-Y gastric bypass [RYGB]) and sleeve gastrectomy (SG), both techniques by videolaparoscopy.

METHODS

The study included 100 consecutive patients who underwent RYGB and SG techniques, totaling 200 patients, and were followed up for 60 months, from June 2013 to July 2018.

RESULTS

The frequency of gastroesophageal reflux disease (GERD) was lower in RYGB patients (p<0.05). At 60 months, the %EWL was 77.4±13.3 kg (RYGB) versus 80.5±17.5 kg (SG) (p<0.05). The BMI data were statistically significantly different between groups after 5 years (28.5±3.9 kg/m2 in RYGB and 31.9±5.3 kg/m2 in SG groups, p<0.05). During the follow-up, the RYGB showed higher %EWL compared to the SG (at 60 months, 80.1% vs. 59.1%, respectively, p<0.05). The %TWL was 30% for the RYGB and 19.7% for the SG (p<0.05). The RYGB had a lower frequency of reflux esophagitis and Barrett's esophagus.

CONCLUSIONS

The RYGB technique showed greater absolute weight loss, %TWL, BMI reduction, and %EWL in higher obesity classes compared to the SG technique. Additionally, RYGB had a lower frequency of reflux esophagitis and Barrett's esophagus.

摘要

背景

在全球20亿超重人群中,巴西的肥胖人数排名第五,因此需要针对肥胖的治疗方案。

目的

本研究的目的是比较接受胃旁路手术(Roux-en-Y胃旁路术[RYGB])和袖状胃切除术(SG)的肥胖患者的总体重减轻百分比(%TWL)、体重指数(BMI)变化、超重减轻百分比(%EWL)、反流性食管炎的发生率以及巴雷特食管的发生情况,这两种手术均通过视频腹腔镜进行。

方法

该研究纳入了100例连续接受RYGB和SG手术的患者,共计200例患者,并于2013年6月至2018年7月进行了60个月的随访。

结果

RYGB患者的胃食管反流病(GERD)发生率较低(p<0.05)。在60个月时,%EWL为77.4±13.3千克(RYGB)对80.5±17.5千克(SG)(p<0.05)。5年后两组之间的BMI数据在统计学上有显著差异(RYGB组为28.5±3.9千克/平方米,SG组为31.9±5.3千克/平方米,p<0.05)。在随访期间,与SG相比,RYGB显示出更高的%EWL(在60个月时,分别为80.1%对59.1%,p<0.05)。RYGB的%TWL为30%,SG为19.7%(p<0.05)。RYGB的反流性食管炎和巴雷特食管发生率较低。

结论

与SG技术相比,RYGB技术在更高肥胖等级的患者中显示出更大的绝对体重减轻、%TWL、BMI降低和%EWL。此外,RYGB的反流性食管炎和巴雷特食管发生率较低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8629/12210394/2b9ee11498a4/0102-6720-abcd-38-e1885-gf01.jpg

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