Auger Nathalie, Youssef Mayaline, Ayoub Aimina, Israël Mimi, Steiger Howard, Low Nancy, Côté-Corriveau Gabriel
University of Montreal Hospital Research Centre, Montreal, Canada.
Institut national de santé publique du Québec, Montreal, Canada.
Stress Health. 2025 Aug;41(4):e70071. doi: 10.1002/smi.70071.
Adolescent mental health was a major problem during the COVID-19 pandemic. We determined the extent to which adolescents with a history of adversity were at risk of mental health hospitalization during the pandemic. We conducted a longitudinal cohort study of 303,378 adolescents from Quebec, Canada, who were age 10-14 years at the start of the pandemic. The main exposure was early life adversity, which included childhood adversity as well as maternal history of adversity or mental illness. The main outcome was hospitalization for a psychiatric disorder, substance use disorder, or suicide attempt between March 2020 and March 2023. We used Cox regression models to compute adjusted hazard ratios (HR) and 95% confidence intervals (CI) for the association of adversity with risk of mental health admission during the pandemic. Adolescents with a history of childhood adversity were 6-9 times more likely to be admitted for a psychiatric disorder (HR 5.79, 95% CI 4.82-6.95), substance use disorder (HR 8.89, 95% CI 6.36-12.43), or suicide attempt (HR 6.93, 95% CI 4.85-9.90) during the pandemic, compared with other adolescents. Adolescents whose mothers experienced adversity or whose mothers had mental illness were 2-6 times more likely to be admitted for mental disorders. Associations were present for both sexes, although adversity was particularly associated with substance use disorders among males. Having a history of childhood or maternal adversity was a strong risk factor for mental health hospitalization among adolescents during the pandemic.
青少年心理健康是新冠疫情期间的一个主要问题。我们确定了有逆境史的青少年在疫情期间心理健康住院的风险程度。我们对来自加拿大魁北克的303378名青少年进行了一项纵向队列研究，这些青少年在疫情开始时年龄为10至14岁。主要暴露因素是早期生活逆境，包括童年逆境以及母亲的逆境或精神疾病史。主要结局是2020年3月至2023年3月期间因精神疾病、物质使用障碍或自杀未遂而住院。我们使用Cox回归模型来计算逆境与疫情期间心理健康入院风险之间关联的调整后风险比（HR）和95%置信区间（CI）。与其他青少年相比，有童年逆境史的青少年在疫情期间因精神疾病（HR 5.79，95% CI 4.82 - 6.95）、物质使用障碍（HR 8.89，95% CI 6.36 - 12.43）或自杀未遂（HR 6.93，95% CI 4.85 - 9.90）而入院的可能性高6至9倍。母亲经历过逆境或患有精神疾病的青少年因精神障碍入院的可能性高2至6倍。两性均存在这种关联，尽管逆境在男性中尤其与物质使用障碍相关。有童年或母亲逆境史是疫情期间青少年心理健康住院的一个强有力的风险因素。
