Ko Albert, Zhang Yiwen, Giovannucci Edward
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Prev Med. 2025 Sep;198:108350. doi: 10.1016/j.ypmed.2025.108350. Epub 2025 Jul 3.
To study the association of intensity and volume of individual physical activities with mortality risk among US older males.
We prospectively followed 10,218 men in Health Professionals Follow-up Study (2012-2022) who were free of diabetes, cardiovascular disease or cancer at baseline. Intensity of biking, swimming and tennis was assessed using biennial questionnaires and categorized into two intensity groups: low intensity, medium/high intensity. Cumulative averaged physical activity volume was classified based on tertiles: low volume, medium/high volume. We examined joint associations of physical activity intensity and volume with mortality using multivariable-adjusted Cox proportional hazards regression models to estimate hazard ratios (HRs) and 95 % CI.
During 89,168 person-years of follow-up (mean [SD] age at baseline, 73.8 [6.9] years [range, 65-102 years]), 2303 deaths were documented. Medium/high intensity performed at medium/high volume was suggestively associated with reduced mortality risk for biking (HR: 0.83 [95 % CI: 0.73, 0.94]), swimming (HR: 0.81 [95 % CI: 0.63, 1.03]), and tennis (HR: 0.83 [95 % CI: 0.65, 1.05]), compared with non-participation in these activities, respectively. Further, specific levels of intensity and volume in biking (medium/high intensity and low volume: HR 0.89 [95 % CI: 0.76, 1.05]), swimming (low intensity and low volume: HR 0.77 [95 % CI: 0.57, 1.06]), and tennis (low intensity and medium/high volume: HR 0.49 [95 % CI: 0.23, 1.01]) were suggestively associated with reduced mortality risk compared with non-participants.
Both physical activity intensity and volume inform on mortality risk for biking, tennis and swimming, highlighting the necessity of examining both factors in future research.
研究美国老年男性个体体育活动的强度和量与死亡风险之间的关联。
我们在健康专业人员随访研究（2012 - 2022年）中对10218名男性进行了前瞻性随访，这些男性在基线时无糖尿病、心血管疾病或癌症。通过每两年一次的问卷评估骑自行车、游泳和网球的强度，并将其分为两个强度组：低强度、中等/高强度。累积平均体育活动量根据三分位数进行分类：低量、中等/高量。我们使用多变量调整的Cox比例风险回归模型来估计风险比（HRs）和95%置信区间（CI），以研究体育活动强度和量与死亡率的联合关联。
在89168人年的随访期间（基线时的平均[标准差]年龄为73.8[6.9]岁[范围为65 - 102岁]），记录了2303例死亡。与不参与这些活动相比，中等/高强度且中等/高量的骑自行车（HR：0.83[95%CI：0.73, 0.94]）、游泳（HR：0.81[95%CI：0.63, 1.03]）和网球（HR：0.83[95%CI：0.65, 1.05]）与死亡风险降低存在提示性关联。此外，与不参与者相比，骑自行车（中等/高强度和低量：HR 0.89[95%CI：0.76, 1.05]）、游泳（低强度和低量：HR 0.77[95%CI：0.57, 1.06]）和网球（低强度和中等/高量：HR 0.49[95%CI：0.23, 1.01]）的特定强度和量水平与死亡风险降低存在提示性关联。
体育活动的强度和量均与骑自行车、网球和游泳的死亡风险相关，这突出了在未来研究中同时考察这两个因素的必要性。
