Kelly H B, Freeman H L, Banning B, Schiff A A
Int Pharmacopsychiatry. 1977;12(1):54-64. doi: 10.1159/000468286.
The clinical and social effects of flupenthixol decanoate and fluphenazine decanoate were compared in the maintenance treatment of a population of chronic schizophrenic out-patients over a period of 9 months. The results failed to show significant difference between the treatments, and in particular, reports suggesting specific advantages for flupenthixol decanoate in alleviating the negative symptoms of apathy, anergia and depression in chronic schizophrenics were not confirmed. It seems that chronic schizophrenic patients who are well established on one depot preparation are unlikely to be benefited by being changed to the alternative.
在9个月的时间里，对一组慢性精神分裂症门诊患者进行维持治疗，比较了癸酸氟哌噻吨和癸酸氟奋乃静的临床及社会效应。结果显示两种治疗方法之间无显著差异，特别是，关于癸酸氟哌噻吨在缓解慢性精神分裂症患者的冷漠、无活力和抑郁等阴性症状方面具有特定优势的报道未得到证实。似乎已经适应一种长效制剂的慢性精神分裂症患者换用另一种制剂不太可能从中获益。
