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胃肠道管理增强术后恢复方案可改善接受后路腰椎椎间融合术患者的术后恢复情况。

Gastrointestinal Management Enhanced Recovery after Surgery Protocol Improves Postoperative Recovery in Patients Undergoing Posterior Lumbar Interbody Fusion.

作者信息

Zeng Cheng, Ding Hongtao, Xu Andrew Y, Wu Jiayuan, Diebo Bassel G, Daniels Alan H, He Da

机构信息

Department of Spine Surgery, Beijing Jishuitan Hospital, Capital Medical University, Beijing, PR China.

Department of Orthopedics, Warren Alpert Medical School, Brown University, Providence, RI, USA.

出版信息

Global Spine J. 2025 Jul 7:21925682251356905. doi: 10.1177/21925682251356905.

Abstract

Study designRetrospective Study.ObjectivesPostoperative gastrointestinal dysfunction (POGD) adversely affects patient outcomes. ERAS protocols can improve postoperative outcomes by optimizing gastrointestinal (GI) function. This study aims to evaluate the effectiveness of a GI management ERAS protocol in patients with posterior lumbar interbody fusion (PLIF) surgery.MethodsA retrospective analysis was conducted on patients who underwent PLIF between 2017 and 2020 in a single institution. The control group included patients treated before the institution adopted updated ERAS protocols including GI management, and the intervention group included patients treated after, with special intestinal preparation, intake and GI management. Demographic data, intraoperative and postoperative variables, and GI assessments were analyzed.ResultsThe study included 163 patients: 78 in the intervention group and 85 in the control group. No significant differences were found in demographics, perioperative variables, comorbidities, or postoperative VAS and ODI scores. In the intervention group, the postoperative length of stay and ambulation time were reduced by 45.0% ( = 0.02) and 68.0% ( = 0.01), respectively. They also had lower rates of postoperative complications, including poor feeding (11.6%, = 0.02), nausea and vomiting (11.6%, = 0.03), hypoalbuminemia (10.3%, = 0.04), and constipation (24.4%, < 0.01). The time to first postoperative flatus and defecation was reduced by 41.5% ( < 0.01) and 30.1% ( = 0.02). PAC-SYM was decreased by 31.9% ( < 0.01), and GIS was decreased by 41.2% ( < 0.01).ConclusionsImplementing a GI management ERAS protocol accelerates postoperative recovery in PLIF surgery. Integrating these strategies into standard perioperative care may not only diminish the incidence of postoperative GI dysfunction but also reduce complications, enhancing surgical outcomes.

摘要

研究设计

回顾性研究。

目的

术后胃肠功能障碍(POGD)对患者预后产生不利影响。加速康复外科(ERAS)方案可通过优化胃肠(GI)功能改善术后预后。本研究旨在评估胃肠管理ERAS方案在腰椎后路椎间融合术(PLIF)患者中的有效性。

方法

对2017年至2020年在单一机构接受PLIF手术的患者进行回顾性分析。对照组包括在该机构采用包括胃肠管理在内的更新ERAS方案之前接受治疗的患者,干预组包括之后接受治疗的患者,采用特殊的肠道准备、摄入和胃肠管理。分析人口统计学数据、术中及术后变量以及胃肠评估结果。

结果

本研究纳入163例患者:干预组78例,对照组85例。在人口统计学、围手术期变量、合并症或术后视觉模拟评分(VAS)和功能障碍指数(ODI)评分方面未发现显著差异。在干预组中,术后住院时间和下床活动时间分别减少了45.0%(P = 0.02)和68.0%(P = 0.01)。他们术后并发症的发生率也较低,包括喂养困难(11.6%,P = 0.02)、恶心和呕吐(11.6%,P = 0.03)、低蛋白血症(10.3%,P = 0.04)和便秘(24.4%,P < 0.01)。首次术后排气和排便时间分别减少了41.5%(P < 0.01)和30.1%(P = 0.02)。术后胃肠症状评分(PAC - SYM)降低了31.9%(P < 0.01),胃肠功能评分(GIS)降低了41.2%(P < 0.01)。

结论

实施胃肠管理ERAS方案可加速PLIF手术的术后恢复。将这些策略纳入标准围手术期护理不仅可降低术后胃肠功能障碍的发生率,还可减少并发症,提高手术效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c472/12237931/bae141ca502e/10.1177_21925682251356905-fig1.jpg

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