Mattox K L, Holzman M, Pickard L R, Beall A C, DeBakey M E
Ann Thorac Surg. 1985 Nov;40(5):456-63. doi: 10.1016/s0003-4975(10)60100-2.
Debate exists with regard to the use of pump bypass, shunt bypass, or clamp/repair techniques in treating injuries to the descending thoracic aorta. The objective in using any of these techniques is to minimize the complications of paraplegia and renal failure, while achieving the lowest possible mortality. During an eighteen-year period, 45 patients were seen with acute blunt injury to the descending thoracic aorta. The shunt bypass method of repair was used in 1; pump bypass in 8; and clamp/repair in 23. There were desperate unsuccessful attempts to resuscitate and control hemorrhage in 13 patients, 1 of whom was placed on portable pump bypass. Thirty-two patients survived resuscitation and operation, and 26 were long-term survivors. Among surviving patients with permanent paraplegia, 2 underwent pump bypass and 1, the clamp/repair technique. Four other patients were seen with paraplegia or paresis and had reversal of the paralysis. The clamp/repair technique was used in these patients with clamp times ranging from 35 to 62 minutes (mean, 47.4 +/- 13.3 minutes). Renal failure did not occur in any patient, despite clamp times of up to 62 minutes (mean, 37.5 minutes). Excluding patients seen in a moribund condition, mortality most often was secondary to neurological or multisystem injury. Debate continues concerning intraoperative management of this highly lethal vascular injury. The data presented here support the historical composite experience that clamp/repair is a safe and efficacious technique that minimizes paraplegia and mortality.
在治疗胸降主动脉损伤时,对于使用泵旁路、分流旁路或钳夹/修复技术存在争议。使用这些技术的目的是将截瘫和肾衰竭的并发症降至最低,同时实现尽可能低的死亡率。在18年期间,共诊治了45例胸降主动脉急性钝性损伤患者。其中1例采用分流旁路修复法;8例采用泵旁路;23例采用钳夹/修复法。有13例患者在复苏和控制出血方面进行了绝望但未成功的尝试,其中1例使用了便携式泵旁路。32例患者复苏和手术后存活,26例为长期存活者。在存活的永久性截瘫患者中,2例采用泵旁路,1例采用钳夹/修复技术。另有4例患者出现截瘫或轻瘫,但随后瘫痪症状逆转。这些患者采用钳夹/修复技术,钳夹时间为35至62分钟(平均47.4±13.3分钟)。尽管钳夹时间长达62分钟(平均37.5分钟),但没有患者发生肾衰竭。排除濒死状态的患者,死亡率最常见的原因是神经或多系统损伤。关于这种高致死性血管损伤的术中管理,争议仍在继续。此处呈现的数据支持了钳夹/修复是一种安全有效的技术,可将截瘫和死亡率降至最低的历史综合经验。