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医用大麻图书馆:建立一个关于大麻治疗活性研究文章的精选数据库。

Medical Cannabis Library: development of a curated database for research articles on cannabis therapeutic activity.

作者信息

Rodin Dmitry, Maizels Yael, Koman Igor

机构信息

Institute for Personalized and Translational Medicine, Ariel University, Ariel, Israel.

Institute for Personalized and Translational Medicine and Department of Molecular Biology, Faculty of Natural Sciences, Ariel University, Ariel, Israel.

出版信息

J Cannabis Res. 2025 Jul 7;7(1):39. doi: 10.1186/s42238-025-00295-7.

DOI:10.1186/s42238-025-00295-7
PMID:40624604
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12236019/
Abstract

The Medical Cannabis Library (MCL) is a curated database designed to simplify the search for cannabis-related therapeutic research. Addressing the challenge of navigating vast and mixed-quality literature, the MCL consolidates over 11,000 relevant publications from Pubmed, focusing on cannabinoids as therapeutic agents. It features an advanced search interface allowing users to find information by diseases, conditions, symptoms, syndromes, and cannabinoids. The database also categorizes the relationship between cannabinoids and medical conditions as positive, negative, or neutral using natural language processing. This tool streamlines access to cannabis research, aiding professionals in understanding its therapeutic potential across various clinical indications. The MCL represents a significant advancement in organizing and accessing scientific knowledge in the field of medical cannabis.

摘要

医用大麻图书馆(MCL)是一个经过精心策划的数据库,旨在简化对大麻相关治疗研究的搜索。为应对海量且质量参差不齐的文献所带来的挑战,MCL整合了来自PubMed的11000多篇相关出版物,重点关注大麻素作为治疗剂的研究。它具有先进的搜索界面,允许用户按疾病、病症、症状、综合征和大麻素查找信息。该数据库还使用自然语言处理将大麻素与医疗状况之间的关系分类为阳性、阴性或中性。这个工具简化了对大麻研究的获取,帮助专业人员了解其在各种临床适应症中的治疗潜力。MCL代表了医用大麻领域在组织和获取科学知识方面的重大进步。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27cd/12236019/c3c30273ef35/42238_2025_295_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27cd/12236019/8fec31d4eee7/42238_2025_295_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27cd/12236019/c3c30273ef35/42238_2025_295_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27cd/12236019/8fec31d4eee7/42238_2025_295_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27cd/12236019/c3c30273ef35/42238_2025_295_Fig2_HTML.jpg

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本文引用的文献

1
Bibliometric Analysis of Research: Trends, Challenges, and Future Directions.研究的文献计量分析:趋势、挑战与未来方向
Cannabis Cannabinoid Res. 2024 Feb;9(1):21-34. doi: 10.1089/can.2023.0200. Epub 2024 Jan 19.
2
Cannabis Science and Therapeutics: An Overview for Clinicians.大麻科学与治疗学:临床医师概览。
J Clin Pharmacol. 2024 May;64(5):499-513. doi: 10.1002/jcph.2400. Epub 2024 Jan 17.
3
A Mapping Literature Review of Medical Cannabis Clinical Outcomes and Quality of Evidence in Approved Conditions in the USA from 2016 to 2019.
2016年至2019年美国已批准条件下医用大麻临床结果及证据质量的映射文献综述
Med Cannabis Cannabinoids. 2021 Feb 25;4(1):21-42. doi: 10.1159/000515069. eCollection 2021 Jun.
4
CANNUSE, a database of traditional Cannabis uses-an opportunity for new research.大麻用途传统知识数据库(CANNUSE)——新研究的契机。
Database (Oxford). 2021 May 1;2021. doi: 10.1093/database/baab024.
5
Association Between Recreational Marijuana Legalization in the United States and Changes in Marijuana Use and Cannabis Use Disorder From 2008 to 2016.美国休闲大麻合法化与 2008 年至 2016 年期间大麻使用和大麻使用障碍变化的关联。
JAMA Psychiatry. 2020 Feb 1;77(2):165-171. doi: 10.1001/jamapsychiatry.2019.3254.
6
Translational Investigation of the Therapeutic Potential of Cannabidiol (CBD): Toward a New Age.翻译为简体中文后的文本如下: 大麻二酚(CBD)治疗潜力的转化研究:迈向新时代。
Front Immunol. 2018 Sep 21;9:2009. doi: 10.3389/fimmu.2018.02009. eCollection 2018.
7
Cannabinoids and cancer pain: A new hope or a false dawn?大麻素与癌症疼痛:新的希望还是虚幻曙光?
Eur J Intern Med. 2018 Mar;49:30-36. doi: 10.1016/j.ejim.2018.01.020.
8
Cannabidiol in patients with seizures associated with Lennox-Gastaut syndrome (GWPCARE4): a randomised, double-blind, placebo-controlled phase 3 trial.Lennox-Gastaut 综合征相关癫痫患儿中使用大麻二酚治疗的随机、双盲、安慰剂对照 3 期临床试验(GWPCARE4)
Lancet. 2018 Mar 17;391(10125):1085-1096. doi: 10.1016/S0140-6736(18)30136-3. Epub 2018 Jan 26.
9
Cannabis and Pain: A Clinical Review.大麻与疼痛:一项临床综述
Cannabis Cannabinoid Res. 2017 May 1;2(1):96-104. doi: 10.1089/can.2017.0017. eCollection 2017.
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Neurotherapeutics. 2015 Oct;12(4):825-36. doi: 10.1007/s13311-015-0387-1.