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在一项针对有药物滥用问题的青年成年人父母的支持项目随机对照试验中,影响结果的潜在预测因素。

Potential predictors affecting outcomes in a randomized controlled trial of support programs for parents of young adults with hazardous substance use.

作者信息

Siljeholm Ola, Hammarberg Anders

机构信息

Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, & Stockholm Health Care Services, Region Stockholm, Stockholm, Sweden.

出版信息

Addict Sci Clin Pract. 2025 Jul 10;20(1):53. doi: 10.1186/s13722-025-00582-x.

Abstract

BACKGROUND

There is a lack of research on which specific factors that predict positive outcomes in support programs for concerned significant others (CSOs) to individuals with substance use disorders (SUDs). The aim of the study was to investigate predictors of positive outcomes among young adults in the areas of: treatment seeking, decreased substance use, and improved parent-young adult relationships. Outcomes were assessed at 24-weeks following a randomized controlled trial (RCT) comparing Community Reinforcement and Family Training (CRAFT) and manualized counselling for parents of young adults (18-24 years) with hazardous substance use.

METHODS

A secondary analysis from an RCT including 113 parents (92% female) of young adults (87% male) recruited from two outpatient clinics for young adults in Stockholm, Sweden, subsequently nationwide. Clinical and sociodemographic predictors of treatment entry, substance use, and relationship happiness at 24 weeks follow-up were assessed using linear and logistic mixed-effects models.

RESULTS

Previous young adult treatment engagement and higher parental self-efficacy were significant predictors of treatment entry, explaining 16% of the variance. Baseline alcohol and substance use consistently predicted higher use over time across measures. Parental stress showed complex associations: higher stress predicted reduced substance use in some models but increased use in others. For the measure of relationship happiness, baseline scores were the strongest predictor.

CONCLUSIONS

Taken together, the findings suggest promising targets for tailored support programs for parents of young adults with SUD, such as components designed to enhance parental self-efficacy.

TRIAL REGISTRATION

ISRCTN12212515 https://www.isrctn.com/ISRCTN12212515 . Submitted November 7th, 2018, registered March 4th, 2019.

摘要

背景

对于物质使用障碍(SUD)患者的相关重要他人(CSO)支持项目中,哪些特定因素能预测积极结果的研究尚显不足。本研究旨在调查年轻成年人在寻求治疗、减少物质使用以及改善亲子关系等方面积极结果的预测因素。在一项随机对照试验(RCT)的24周后对结果进行评估,该试验比较了社区强化和家庭训练(CRAFT)与针对有危险物质使用问题的18 - 24岁年轻成年人父母的手册化咨询。

方法

对一项RCT进行二次分析,该RCT纳入了从瑞典斯德哥尔摩两家针对年轻成年人的门诊诊所招募的113名年轻成年人的父母(92%为女性),随后扩展至全国范围。使用线性和逻辑混合效应模型评估24周随访时治疗参与、物质使用和关系满意度的临床及社会人口学预测因素。

结果

之前年轻成年人的治疗参与度和较高的父母自我效能感是治疗参与的显著预测因素,解释了16%的方差。基线酒精和物质使用在各项测量中始终预测随着时间推移使用量会更高。父母压力呈现复杂的关联:在某些模型中较高的压力预测物质使用减少,但在其他模型中则预测使用增加。对于关系满意度的测量,基线分数是最强的预测因素。

结论

综合来看,研究结果表明为患有SUD的年轻成年人父母量身定制支持项目有了有前景的目标,例如旨在提高父母自我效能感的组成部分。

试验注册

ISRCTN12212515 https://www.isrctn.com/ISRCTN12212515 。于2018年11月7日提交,2019年3月4日注册。

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