Gupta Rahul, Mehmood Yasir, Mahajan Arti, Sharma Sindhu
Department of Urology and Renal Transplant, Government Medical College, Jammu, Jammu and Kashmir, India.
Department of Anesthesia, Government Medical College, Jammu, Jammu and Kashmir, India.
J Midlife Health. 2025 Apr-Jun;16(2):215-217. doi: 10.4103/jmh.jmh_38_25. Epub 2025 Jun 23.
Encrusted cystitis (EC) is a rare clinical entity, with the first description dating back to 1914 by Francois J. This variety of debilitating and rare cystitis is caused by urea-splitting , especially type 2B2 (CBGD2). Patients with prior urinary trauma, a history of intravesical bacillus Calmette-Guérin instillation, or chemotherapy are at higher risk for developing EC. Clinical presentation varies from dysuria, pain, hematuria, or passage of mucus or calcified mucopurulent stones. Diagnosis of Encrusted cystitis is done after excluding the other pathologies and is confirmed on isolation of Corynebacterium Type 2B2 organism and its characteristic features on radiotherapy. Medical management involves glycopeptide antibiotics and acidification of urine, either topical or systemic. Surgical treatment is done in rare cases with failed medical management or spontaneous bladder rupture. We report a rare case of morbid EC who required cystectomy and diversion.
结痂性膀胱炎（EC）是一种罕见的临床病症，首次描述可追溯到1914年由弗朗索瓦·J所作。这种使人衰弱的罕见膀胱炎是由尿素分解引起的，尤其是2B2型（CBGD2）。既往有尿路创伤、膀胱内卡介苗灌注史或化疗史的患者发生EC的风险更高。临床表现从尿痛、疼痛、血尿或排出黏液或钙化的黏液脓性结石不等。结痂性膀胱炎的诊断在排除其他病理情况后进行，并通过分离2B2型棒状杆菌及其在放射治疗中的特征性表现得以证实。药物治疗包括糖肽类抗生素以及局部或全身的尿液酸化。在药物治疗失败或发生自发性膀胱破裂的罕见情况下进行手术治疗。我们报告了一例需要进行膀胱切除术和尿流改道的重症EC罕见病例。
