Kazui T, Kimura N, Yamada O, Komatsu S
Second Department of Surgery, Sapporo Medical University School of Medicine, Japan.
Ann Thorac Surg. 1994 Apr;57(4):904-11. doi: 10.1016/0003-4975(94)90201-1.
The surgical results observed in 80 patients with aneurysms of the aortic arch who underwent an operation between January 1986 and the end of August 1992 were analyzed by multivariate analysis to identify predictors of high operative risk. All operations were performed using a cardiopulmonary bypass technique, blood cardioplegia for myocardial protection, and selective cerebral perfusion to prevent cerebral ischemia during aortic arch repair. The overall early (30-day) mortality rate was 16.3%. A severe stroke occurred postoperatively in 1 patient (1.3%). The 5-year survival rate was 73% +/- 5%, as determined by the Kaplan-Meier method. Multivariate analysis revealed that the presence of critical cardiopulmonary dysfunction preoperatively and the need for reoperation were significant independent predictors. Of the 63 (79%) patients who were free of these risks, only 3 (4.8%) died. The findings from the present study indicate that, currently, early mortality is relatively low for all patients who undergo operations for aneurysm of the aortic arch, unless they are in a critical condition preoperatively or unless they are undergoing a reoperation.
对1986年1月至1992年8月底接受手术的80例主动脉弓动脉瘤患者的手术结果进行多因素分析,以确定高手术风险的预测因素。所有手术均采用体外循环技术、冷血心脏停搏液保护心肌,并在主动脉弓修复期间进行选择性脑灌注以预防脑缺血。总体早期(30天)死亡率为16.3%。术后1例患者(1.3%)发生严重卒中。根据Kaplan-Meier法确定的5年生存率为73%±5%。多因素分析显示,术前存在严重心肺功能障碍和需要再次手术是显著的独立预测因素。在63例(79%)无这些风险的患者中,只有3例(4.8%)死亡。本研究结果表明,目前,对于所有接受主动脉弓动脉瘤手术的患者,除非术前病情危急或正在接受再次手术,早期死亡率相对较低。