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糖化血红蛋白A1用于糖尿病护理质量控制:门诊诊所的横断面研究。

Glycosylated hemoglobin A1 used in quality-control of diabetes care: a cross-sectional study in an outpatient clinic.

作者信息

Matzen L E, Larsen J B, Frøland A

出版信息

Diabetes Res. 1985 Sep;2(5):243-7.

PMID:4064476
Abstract

HBA1 was used to evaluate the quality of treatment and regulation in 163 insulin treated diabetes patients. The mean of HBA1 in all patients was 11.2 +/- 2.4%. Only 24% of the patients had HBA1 values below the mean + 3 SD of non diabetics. Patients with high values of HBA1 were controlled and treated more intensively than those with lower or normal values. They were also seen more frequently at the outpatient clinic, their insulin doses were larger, and they took more frequent insulin injections. 63% of the patients practised home monitoring of blood glucose, but they were not better controlled than those, who did not. In some of the patients conspicuous discrepancies were found between high HBA1 percentages and low blood glucose values measured at the outpatient clinic. It is concluded, that home monitoring of blood glucose, frequent visits to an outpatient clinic, and 2 daily insulin injections do not appreciably improve diabetes control, and that other approaches are needed, e.g., greater co-operation by the patients in frequent adjustments of treatment between clinic visits.

摘要

采用糖化血红蛋白A1(HBA1)评估163例接受胰岛素治疗的糖尿病患者的治疗及病情控制质量。所有患者的HBA1均值为11.2±2.4%。仅24%的患者HBA1值低于非糖尿病患者均值加3个标准差。HBA1值高的患者比HBA1值低或正常的患者接受更严格的控制和治疗。他们在门诊就诊更频繁,胰岛素剂量更大,注射胰岛素更频繁。63%的患者进行家庭血糖监测,但他们的病情控制情况并不比未进行家庭血糖监测的患者更好。在一些患者中,门诊测得的高HBA1百分比与低血糖值之间存在明显差异。得出的结论是,家庭血糖监测、频繁门诊就诊及每日两次胰岛素注射并不能显著改善糖尿病控制情况,需要采取其他方法,例如患者在门诊就诊期间更积极配合频繁调整治疗方案。

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