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埃博拉病毒的耐热性及灭活

Thermal tolerance and inactivation of Ebola virus.

作者信息

Gao Xiaoxiao, Peng Cheng, Pei Rongjuan

机构信息

State Key Laboratory of Virology and Biosafety, Center for Biosafety Mega-Science, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430207, China.

State Key Laboratory of Virology and Biosafety, Center for Biosafety Mega-Science, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430207, China.

出版信息

Virol Sin. 2025 Aug;40(4):669-671. doi: 10.1016/j.virs.2025.07.004. Epub 2025 Jul 9.

DOI:10.1016/j.virs.2025.07.004
PMID:40645504
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12414411/
Abstract

• The investigation demonstrated a high level of tolerance of EBOV to thermal disinfection. • A water-bath is recommended and the tubes should be fully submerged during the process. • The established inactivation guidelines should be followed very strictly.

摘要

• 调查表明埃博拉病毒对热消毒具有高度耐受性。

• 建议使用水浴,并且在此过程中试管应完全浸没。

• 应严格遵循既定的灭活指南。

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本文引用的文献

1
Ebola virus VP35 perturbs type I interferon signaling to facilitate viral replication.埃博拉病毒 VP35 扰乱 I 型干扰素信号转导以促进病毒复制。
Virol Sin. 2023 Dec;38(6):922-930. doi: 10.1016/j.virs.2023.10.004. Epub 2023 Oct 13.
2
Renaming of genera Ebolavirus and Marburgvirus to Orthoebolavirus and Orthomarburgvirus, respectively, and introduction of binomial species names within family Filoviridae.将埃博拉病毒属和马尔堡病毒属分别更名为正埃博拉病毒属和正马尔堡病毒属,并在丝状病毒科内引入双名种名。
Arch Virol. 2023 Aug 3;168(8):220. doi: 10.1007/s00705-023-05834-2.
3
Establishment of an Inactivation Method for Ebola Virus and SARS-CoV-2 Suitable for Downstream Sequencing of Low Cell Numbers.
建立一种适用于低细胞数下游测序的埃博拉病毒和严重急性呼吸综合征冠状病毒2(SARS-CoV-2)灭活方法。
Pathogens. 2023 Feb 17;12(2):342. doi: 10.3390/pathogens12020342.
4
Stability of SARS-CoV-2 on the Surfaces of Three Meats in the Setting That Simulates the Cold Chain Transportation.模拟冷链运输环境下严重急性呼吸综合征冠状病毒2在三种肉类表面的稳定性
Virol Sin. 2021 Oct;36(5):1069-1072. doi: 10.1007/s12250-021-00367-x. Epub 2021 Apr 8.
5
Heat Inactivation of Different Types of SARS-CoV-2 Samples: What Protocols for Biosafety, Molecular Detection and Serological Diagnostics?不同类型 SARS-CoV-2 样本的热失活:生物安全、分子检测和血清学诊断的哪些方案?
Viruses. 2020 Jul 7;12(7):735. doi: 10.3390/v12070735.
6
Effective Chemical Inactivation of Ebola Virus.埃博拉病毒的有效化学灭活
Emerg Infect Dis. 2016 Jul;22(7):1292-4. doi: 10.3201/eid2207.160233. Epub 2016 Jul 15.
7
Buffer AVL Alone Does Not Inactivate Ebola Virus in a Representative Clinical Sample Type.单独使用AVL缓冲液不能使典型临床样本类型中的埃博拉病毒失活。
J Clin Microbiol. 2015 Oct;53(10):3148-54. doi: 10.1128/JCM.01449-15. Epub 2015 Jul 15.
8
Thermal stability of structurally different viruses with proven or potential relevance to food safety.具有已证实或潜在食品安全相关性的结构不同病毒的热稳定性。
J Appl Microbiol. 2012 May;112(5):1050-7. doi: 10.1111/j.1365-2672.2012.05282.x. Epub 2012 Mar 30.
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Thermostability of subpopulations of H2N3 influenza virus isolates from mallard ducks.鸭源 H2N3 流感病毒分离株亚群的热稳定性。
J Virol. 2010 Sep;84(18):9369-76. doi: 10.1128/JVI.01170-10. Epub 2010 Jul 7.
10
Influence of heat transfer with tube methods on measured thermal inactivation parameters for Escherichia coli.采用管式方法进行热传递对大肠杆菌热失活参数测量结果的影响。
J Food Prot. 2007 Apr;70(4):851-9. doi: 10.4315/0362-028x-70.4.851.