Haddock Elaine, Feldmann Friederike, Feldmann Heinz
Emerg Infect Dis. 2016 Jul;22(7):1292-4. doi: 10.3201/eid2207.160233. Epub 2016 Jul 15.
Reliable inactivation of specimens before removal from high-level biocontainment is crucial for safe operation. To evaluate efficacy of methods of chemical inactivation, we compared in vitro and in vivo approaches using Ebola virus as a surrogate pathogen. Consequently, we have established parameters and protocols leading to reliable and effective inactivation.
在从高级生物防护设施中取出标本之前进行可靠的灭活对于安全操作至关重要。为了评估化学灭活方法的效果,我们使用埃博拉病毒作为替代病原体比较了体外和体内方法。因此,我们建立了能够实现可靠且有效灭活的参数和方案。