Chen Ying-Chu, Chen Michael, Hsu Yu-Kuei
Department of Chemical Engineering & Biotechnology, National Taipei University of Technology, Taipei City 10608, Taiwan.
Department of Opto-Electronic Engineering, National Dong Hwa University, Hualien 97401, Taiwan.
Nanomaterials (Basel). 2025 Jun 27;15(13):998. doi: 10.3390/nano15130998.
A facile fabrication method was developed for the growth of CuSe nanosheets (NSs) on a Cu foil substrate, enabling dual-functionality as an electrochemical sensor for HO and an active surface-enhanced Raman scattering (SERS) substrate. The process involved the preparation of Cu(OH) nanowires (NWs) via electrochemical oxidation, followed by chemical conversion to CuSe through a selenization process. The morphology, composition, and microstructure of the resulting CuSe NSs were systematically characterized using scanning electron microscopy (SEM), X-ray diffraction (XRD), and X-ray photoelectron spectroscopy (XPS). The CuSe NSs exhibited excellent electrocatalytic activity for HO reduction, achieving a notably low detection limit of 1.25 μM and demonstrating rapid response and high sensitivity with a linear relationship in amperometric detection. Additionally, SERS experiments using Rhodamine B as a probe molecule and the CuSe NS/Cu foil as a substrate displayed outstanding performance, with a detection limit as low as 1 μM. The flower-like structure of the CuSe NSs exhibited linear dependence between analyte concentration and detection signals, along with satisfactory reproducibility in dual-sensing applications. These findings underscore the scalability and potential of this fabrication approach for advanced sensor development.
开发了一种简便的制备方法，用于在铜箔基板上生长硒化铜纳米片（NSs），使其具有作为羟基自由基（HO）电化学传感器和活性表面增强拉曼散射（SERS）基板的双重功能。该过程包括通过电化学氧化制备氢氧化铜纳米线（NWs），然后通过硒化过程将其化学转化为硒化铜。使用扫描电子显微镜（SEM）、X射线衍射（XRD）和X射线光电子能谱（XPS）对所得硒化铜纳米片的形貌、组成和微观结构进行了系统表征。硒化铜纳米片对HO还原表现出优异的电催化活性，实现了低至1.25 μM的显著低检测限，并在安培检测中显示出快速响应和高灵敏度以及线性关系。此外，以罗丹明B为探针分子、硒化铜纳米片/铜箔为基板的SERS实验表现出色，检测限低至1 μM。硒化铜纳米片的花状结构在分析物浓度和检测信号之间表现出线性依赖性，并且在双传感应用中具有令人满意的重现性。这些发现强调了这种制备方法在先进传感器开发方面的可扩展性和潜力。
