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希腊接受慢性血液透析治疗患者的血管通路流行病学

Epidemiology of Vascular Access in Patients Undergoing Chronic Hemodialysis Treatment in Greece.

作者信息

Nousis Athanasios, Tziastoudi Maria, Oustampasidou Niki, Efthymiadi Maria, Divani Maria, Eleftheriadis Theodoros, Stefanidis Ioannis

机构信息

Department of Nephrology, Faculty of Medicine, School of Health Sciences, University of Thessaly, 41500 Larissa, Greece.

出版信息

J Clin Med. 2025 Jun 27;14(13):4571. doi: 10.3390/jcm14134571.

Abstract

Vascular access (VA) is one of the most critical procedures during dialysis for patients with end-stage renal disease (ESRD), as it influences morbidity, mortality, and quality of life. This cross-sectional study analyzed the vascular access epidemiology of patients undergoing chronic HD in 15 nephrology centers across Greece from 2013 to 2019. Data on VA type, demographic characteristics, fatigue severity, and quality of life were gathered from a sample of 373 patients. The prevailing result of this study is that arteriovenous fistula (AVF) was the commonly practiced VA, and its associated survival outcomes were better when compared to arteriovenous grafts (AVGs) and central venous catheters (CVCs). Patients with AVFs had significantly longer survival times (median 165 months) compared to non-fistula access. Furthermore, the degree of fatigue and quality of life were also dependent on the type of VA used, with patients on AVF having lower fatigue levels and better quality of life. Age, gender, and an early nephrologist referral were noted to affect the selection and the rate of maturation of VA. Despite AVF being the preferred VA, late referrals and high initial reliance on CVCs remain challenges. This study underscores the need for early nephrological intervention, surveillance programs, and patient education to optimize vascular access outcomes. Future research should focus on national strategies to reduce CVC-related complications and improve long-term HD care in Greece.

摘要

血管通路(VA)是终末期肾病(ESRD)患者透析过程中最关键的操作之一,因为它会影响发病率、死亡率和生活质量。这项横断面研究分析了2013年至2019年希腊15个肾脏病中心接受慢性血液透析患者的血管通路流行病学情况。从373例患者的样本中收集了关于血管通路类型、人口统计学特征、疲劳严重程度和生活质量的数据。这项研究的主要结果是,动静脉内瘘(AVF)是常用的血管通路,与动静脉移植物(AVG)和中心静脉导管(CVC)相比,其相关的生存结果更好。与非内瘘血管通路相比,有动静脉内瘘的患者生存时间显著更长(中位数为165个月)。此外,疲劳程度和生活质量也取决于所使用的血管通路类型,使用动静脉内瘘的患者疲劳水平较低,生活质量较好。年龄、性别和肾病医生的早期转诊被认为会影响血管通路的选择和成熟率。尽管动静脉内瘘是首选的血管通路,但晚期转诊和对中心静脉导管的高度初始依赖仍然是挑战。这项研究强调了早期肾脏干预、监测计划和患者教育以优化血管通路结果的必要性。未来的研究应侧重于减少希腊中心静脉导管相关并发症和改善长期血液透析护理的国家战略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f607/12249874/e1b4e329a87f/jcm-14-04571-g001.jpg

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