Fram Madeline R, Denney Jeff M, Quinn Kristen H
Section on Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.
J Clin Med. 2025 Jun 28;14(13):4594. doi: 10.3390/jcm14134594.
Previous research has examined the idea of the healthy immigrant effect and its potential application to pregnancy-related hypertensive disorders, particularly inracial and ethnic minority groups. The aim of this study is to examine how nativity, race, and ethnicity are related to prevalence of pregnancy-related hypertensive disorders. A retrospective cohort study was conducted using data from the PRAMS CDC dataset. These data were analyzed via comparisons of prevalence of pregnancy-related hypertensive disorders in foreign and US-born mothers, including subgroup analyses for Black and Hispanic women. : A sample size of 63,648 was analyzed, and revealed significant differences in the prevalence of gestational hypertension between US-born vs. foreign-born Black mothers (12.6% vs. 8.0%, (1, N = 12,046) = 36.92, < 0.001), Hispanic mothers (9.5% vs. 7.2%, (1, N = 11,524) = 18.236, < 0.001), and the larger sample of mothers across all reported racial and ethnic backgrounds (11.0% vs. 7.0%, (1, N = 63,648) = 163.835, < 0.001). The results also revealed a significant difference in the prevalence of hypertension eclampsia between US-born and foreign-born Hispanic mothers (0.8% vs. 0.3%, (1, N = 11,152) = 8.480, = 0.004). The study results showed evidence of significantly lower prevalence of pregnancy-related hypertensive disorders among foreign-born mothers as compared to their US-born counterparts, both in the full study sample and specifically in the subsamples of women who self-identified as Black and women who self-identified as Hispanic. These variances by nativity, race, and ethnicity provide further insight into how the healthy immigrant effect can apply to pregnancy-related hypertensive disorders, particularly for women of racial and ethnic minorities.
以往的研究探讨了健康移民效应的概念及其在妊娠相关高血压疾病中的潜在应用，特别是在种族和少数族裔群体中。本研究的目的是探讨出生地、种族和民族与妊娠相关高血压疾病患病率之间的关系。使用疾病预防控制中心（CDC）的妊娠风险评估监测系统（PRAMS）数据集进行了一项回顾性队列研究。通过比较外国出生和美国出生母亲的妊娠相关高血压疾病患病率对这些数据进行分析，包括对黑人妇女和西班牙裔妇女的亚组分析。分析了63648个样本量，结果显示美国出生与外国出生的黑人母亲之间妊娠高血压患病率存在显著差异（12.6%对8.0%，（1，N = 12046）= 36.92，P < 0.001），西班牙裔母亲之间（9.5%对7.2%，（1，N = 11524）= 18.236，P < 0.001），以及所有报告种族和民族背景的母亲的更大样本（11.0%对7.0%，（1，N = 63648）= 163.835，P < 0.001）。结果还显示美国出生和外国出生的西班牙裔母亲之间子痫前期患病率存在显著差异（0.8%对0.3%，（1，N = 11152）= 8.480，P = 0.004）。研究结果表明，在整个研究样本中，特别是在自我认定为黑人的女性子样本和自我认定为西班牙裔的女性子样本中，外国出生母亲的妊娠相关高血压疾病患病率明显低于美国出生的母亲。这些因出生地、种族和民族而异的差异进一步揭示了健康移民效应如何适用于妊娠相关高血压疾病，特别是对于种族和少数族裔女性。
