Liu Meiyin, Song Yuchen, Liu Meiru, Deng Dongmei, Zhang Wenjiao, Wang Ting, Luo Liqiang
College of Sciences, Shanghai University, Shanghai 200444, China.
School of Health & Social Care, Shanghai Urban Construction Vocational College, Shanghai 201401, China.
Molecules. 2025 Jun 23;30(13):2708. doi: 10.3390/molecules30132708.
Cancer remains a leading cause of morbidity and mortality worldwide. The timely and accurate detection of potential early cancer biomarkers is essential for early cancer diagnosis. In recent years, electrochemical biosensors have garnered significant attention due to their portability, cost-effectiveness, and ease of use. In addition, given their exceptional physicochemical properties, functional nanomaterials have found extensive applications in the field of electrochemical biosensing. This review provides an overview of the basic principles and types of electrochemical biosensors, the classification and properties of functional nanomaterials, and the application of functional nanomaterial-based electrochemical biosensors in the detection of cancer biomarkers. Finally, the prospects and remaining challenges of functional nanomaterial-based electrochemical biosensors in cancer diagnosis are discussed.
癌症仍然是全球发病和死亡的主要原因。及时、准确地检测潜在的早期癌症生物标志物对于早期癌症诊断至关重要。近年来，电化学生物传感器因其便携性、成本效益和易用性而备受关注。此外，由于其优异的物理化学性质，功能纳米材料在电化学生物传感领域得到了广泛应用。本文综述了电化学生物传感器的基本原理和类型、功能纳米材料的分类和性质，以及基于功能纳米材料的电化学生物传感器在癌症生物标志物检测中的应用。最后，讨论了基于功能纳米材料的电化学生物传感器在癌症诊断中的前景和尚存的挑战。
