Cansever Islam, Sogut Ozlem
Central Research Laboratories, Izmir Katip Celebi University, Havaalanı Sosesi Cd. No:33/2, Cigli, 35620, Izmir, Turkey.
Department of Analytical Chemistry, Health Sciences Institute, Ege University, Izmir, Turkey.
Biometals. 2025 Jul 12. doi: 10.1007/s10534-025-00718-1.
This study presents a comprehensive analytical assessment of macro- and micro-element content in Artemisia abrotanum L. harvested during two distinct growth periods-pre-blooming and blooming. Using a validated ICP-MS method, both microwave digestion and infusion extraction techniques were applied to evaluate the elemental composition of the plant. The concentrations of essential, beneficial, and potentially toxic elements-including Na, K, Mg, Ca, Fe, P, S, Al, V, Cr, Mn, Co, Ni, Cu, Zn, As, Se, Sr, Mo, Cd, Ba, Tl, Pb, and U-were determined and compared across harvest times and extraction methods. Chemometric analyses, including principal component and hierarchical cluster analysis, were employed to classify the results and elucidate patterns among the elements and sample types. The findings revealed that the elemental distribution in Artemisia abrotanum L. varies significantly with harvest period and preparation method. Notably, Na, Mn, Ni, Co, As, Se, Sr, and Ba were more abundant during the blooming period, while K, Mg, Ca, Zn, Mo, Cd, and Pb were higher in the pre-blooming period. Differences in P, Fe, Al, V, Cr, and Tl concentrations were primarily attributed to the extraction technique. The study further evaluated the measured element concentrations against updated dietary and toxicological reference values, providing a clearer perspective on the potential health implications of consuming Artemisia abrotanum L. infusions. These results underscore the importance of both harvest timing and preparation method in determining the nutritional and safety profile of medicinal plants.
本研究对在两个不同生长时期（开花前期和开花期）采收的南艾蒿中的常量和微量元素含量进行了全面的分析评估。采用经过验证的电感耦合等离子体质谱法（ICP-MS），运用微波消解和浸提萃取技术来评估该植物的元素组成。测定并比较了必需元素、有益元素和潜在有毒元素（包括钠、钾、镁、钙、铁、磷、硫、铝、钒、铬、锰、钴、镍、铜、锌、砷、硒、锶、钼、镉、钡、铊、铅和铀）在不同采收时间和萃取方法下的含量。采用化学计量学分析方法，包括主成分分析和层次聚类分析，对结果进行分类，并阐明元素和样品类型之间的模式。研究结果表明，南艾蒿中的元素分布随采收期和制备方法的不同而有显著差异。值得注意的是，钠、锰、镍、钴、砷、硒、锶和钡在开花期含量更高，而钾、镁、钙、锌、钼、镉和铅在开花前期含量更高。磷、铁、铝、钒、铬和铊浓度的差异主要归因于萃取技术。该研究还根据最新的饮食和毒理学参考值对测得的元素浓度进行了评估，为饮用南艾蒿浸剂的潜在健康影响提供了更清晰的视角。这些结果强调了采收时间和制备方法在确定药用植物营养和安全状况方面的重要性。
