Prasad Mona, Sandoval Grecio J, Saade George R, Hughes Brenna L, Clifton Rebecca G, Reddy Uma M, Bartholomew Anna, Salazar Ashley, Chien Edward K, Tita Alan T N, Thorp John M, Metz Torri D, Wapner Ronald J, Sabharwal Vishakha, Simhan Hyagriv N, Swamy Geeta K, Heyborne Kent D, Sibai Baha M, Grobman William A, El-Sayed Yasser Y, Casey Brian M, Parry Samuel, Macones George A
Department of Obstetrics and Gynecology of the Ohio State University, Columbus, Ohio, USA.
George Washington University Biostatistics Center, Washington, DC, USA.
Clin Infect Dis. 2025 Jul 14. doi: 10.1093/cid/ciaf266.
In this study, a single hepatitis C virus (HCV) RNA at 2-6 months was sensitive and specific (86.7% and 95% confidence interval [CI], 62.1%-96.3% and 100% and 95% CI, 98.8%-100%, respectively) in identifying perinatal transmission of HCV. No cases of perinatal infection requiring treatment were missed.
在本研究中,2至6个月时检测到的单一丙型肝炎病毒(HCV)RNA在识别HCV围产期传播方面具有敏感性和特异性(分别为86.7%,95%置信区间[CI]:62.1%-96.3%;以及100%,95%CI:98.8%-100%)。未漏诊任何需要治疗的围产期感染病例。