Watts Theresa, Stockman Lauren, Martin Justin, Guilfoyle Sheila, Vergeront James M
MMWR Morb Mortal Wkly Rep. 2017 Oct 27;66(42):1136-1139. doi: 10.15585/mmwr.mm6642a3.
State surveillance during the last 10 years reveals a nationwide increase in hepatitis C virus (HCV) infection among young adults (1). The proportion of infants born to HCV-infected women is also increasing nationally (2). To estimate the proportion of infants born to HCV-infected women and the frequency of confirmed HCV infection in their infants, maternal name and date of birth from HCV reports in the Wisconsin Electronic Disease Surveillance System (WEDSS) were linked to Wisconsin Medicaid data for 2011-2015 births. During this period, in the Wisconsin Medicaid population, the proportion of women who had evidence of HCV infection during pregnancy increased 93%, from 1 in 368 pregnancies to 1 in 192. Among 183 infants born to women with evidence of HCV viremia during pregnancy, 34% received recommended HCV testing (3). Mother-to-infant (vertical) transmission was documented in 4% of infants. Improvements in HCV screening practices among pregnant women and infants could enhance identification of infants at risk for vertical transmission of HCV.
过去10年的国家监测显示，全国范围内年轻成年人丙型肝炎病毒（HCV）感染有所增加（1）。全国范围内，HCV感染女性所生婴儿的比例也在上升（2）。为了估计HCV感染女性所生婴儿的比例及其婴儿确诊HCV感染的频率，将威斯康星州电子疾病监测系统（WEDSS）中HCV报告的母亲姓名和出生日期与2011 - 2015年出生的威斯康星州医疗补助数据相关联。在此期间，在威斯康星州医疗补助人群中，孕期有HCV感染证据的女性比例增加了93%，从368次怀孕中有1例增至192次怀孕中有1例。在孕期有HCV病毒血症证据的女性所生的183名婴儿中，34%接受了推荐的HCV检测（3）。4%的婴儿记录有母婴（垂直）传播。孕妇和婴儿HCV筛查做法的改进可加强对有HCV垂直传播风险婴儿的识别。
