大鼠腹侧前列腺中[1-14C]乙酸盐在体外对脂质亚类的年龄依赖性掺入。
In vitro age-dependent incorporation of [1-14C]acetate into lipid subclasses in rat ventral prostate.
作者信息
Recio M N, Del Hoyo N, Carmena M J, Perez-Albarsanz M A
出版信息
Int J Biochem. 1985;17(10):1129-32. doi: 10.1016/0020-711x(85)90048-5.
The [1-14C]acetate incorporation into different lipid subclasses by the rat prostate gland was lineal between 20 and 80 mg of wet tissue. The in vitro [1-14C]acetate incorporation into lipid subclasses was a development-dependent process. The highest values of [1-14C]acetate incorporation into triacylglycerols, free cholesterol and esterified cholesterol were observed at puberty, but radioactivity incorporation into phospholipids was similar in both prepuberty and puberty, then decreasing in maturity. The relationship between triacylglycerols, free cholesterol and esterified cholesterol with respect to total lipids was about 12, 10 and 3.5%, respectively, values being maintained during the animal development. The in vitro [1-14C]acetate incorporation into lipid subclasses in castrated rats decreased considerably as compared with normal rats.
大鼠前列腺将[1-¹⁴C]乙酸盐掺入不同脂质亚类的过程在20至80毫克湿组织之间呈线性关系。体外将[1-¹⁴C]乙酸盐掺入脂质亚类是一个依赖于发育的过程。在青春期观察到[1-¹⁴C]乙酸盐掺入三酰甘油、游离胆固醇和酯化胆固醇的最高值，但在青春期前和青春期，[1-¹⁴C]乙酸盐掺入磷脂的放射性相似，在成熟期则下降。三酰甘油、游离胆固醇和酯化胆固醇相对于总脂质的比例分别约为12%、10%和3.5%，这些值在动物发育过程中保持稳定。与正常大鼠相比，去势大鼠体外[1-¹⁴C]乙酸盐掺入脂质亚类的量显著降低。
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