Dinsmore W, Callender M E, McMaster D, Todd S J, Love A H
Digestion. 1985;32(4):238-42. doi: 10.1159/000199243.
Alcoholism is occasionally complicated by zinc deficiency. We have assessed the possibility that malabsorption of zinc may be a potential cause. Using a dual isotope absorption technique the absorption of 65Zn in 18 alcoholic patients was 37% (13 +/- SD) and 56% (10 +/- SD) in a normal control group (p less than 0.001). The mean serum zinc in 55 alcoholic patients was 11.6 mumol/l (3.0 +/- SD) and in 36 normal volunteers the mean serum zinc was 13.6 mumol/l (1.8 +/- SD; p less than 0.001). This study suggests that chronic alcohol abuse will decrease the absorption of zinc and this may contribute towards the zinc deficiency occasionally associated with alcoholism.
酒精中毒偶尔会并发锌缺乏。我们评估了锌吸收不良可能是一个潜在原因的可能性。采用双同位素吸收技术，18例酒精性患者对65Zn的吸收率为37%（13±标准差），正常对照组为56%（10±标准差）（p<0.001）。55例酒精性患者的血清锌均值为11.6μmol/l（3.0±标准差），36名正常志愿者的血清锌均值为13.6μmol/l（1.8±标准差；p<0.001）。本研究表明，长期酗酒会降低锌的吸收，这可能是导致偶尔与酒精中毒相关的锌缺乏的原因。
