Sep Milou S C, Veenman Kim, Vinkers Christiaan, Sep Milou S C, Veenman Kim, Habets Philippe C, Bonapersona Valeria, Bakvis Patricia, Bentele Ulrike, Binder Elisabeth, Branje Susan J T, Brückl Tanja, Cornelisse Sandra, Dickinson Philip, Elzinga Bernet M, Evers Andrea W M, Fernández Guillén, Geuze Elbert, Hartman Catharina A, Hermans Erno J, Hernaus Dennis, Joëls Marian, Kaldewaij Reinoud, Meeus Wim H J, Meier Maria, van Middendorp Henriët, Nelemans Stefanie A, Oei Nicole, Oldehinkel Tineke, van Peer Jacobien, Pruessner Jens, Quaedflieg Conny, Roelofs Karin, de Rooij Susanne R, Schwabe Lars, Smeets Tom, Spoormaker Victor, Tollenaar Marieke S, Tutunji Rayyan, Tyborowska Anna, Vinkers Christiaan
Department of Psychiatry, Amsterdam University Medical Centers Location Vrije Universiteit Amsterdam, the Netherlands.
GGZ inGeest Mental Health Care, Amsterdam, the Netherlands.
Neurosci Appl. 2024 Apr 4;3:104063. doi: 10.1016/j.nsa.2024.104063. eCollection 2024.
Our current understanding of the human stress response and its role in health, resilience, and (psycho)pathology stems largely from acute stress studies in controlled laboratory settings. Comparability of findings across these individual studies is comprised, as sample size are often small, between-individual variation in the stress response is large and variation in stress-induction procedures and measurement timing is substantial. To overcome this, 16 research groups across Europe have established the STRESS-EU database. A unique resource with individual participant data ( = 6576) of acute stress studies to promote data reuse and facilitate both meta-analytical and proof-of-principle analyses with high statistical power, that can be hypothesis- or data-driven. This short communication highlights the structure, content, access and contribution procedures and future plans of the STRESS-EU database and invited researchers worldwide to contribute to this data resource.
我们目前对人类应激反应及其在健康、恢复力和（精神）病理学中作用的理解，很大程度上源于在受控实验室环境中进行的急性应激研究。由于这些个体研究的样本量往往较小、应激反应的个体间差异较大，且应激诱导程序和测量时间的差异很大，因此这些个体研究结果的可比性受到影响。为了克服这一问题，欧洲的16个研究小组建立了STRESS-EU数据库。这是一个拥有急性应激研究个体参与者数据（n = 6576）的独特资源，以促进数据重用，并便于进行具有高统计效力的荟萃分析和原理验证分析，这些分析可以是假设驱动或数据驱动的。本简短通讯重点介绍了STRESS-EU数据库的结构、内容、访问和贡献程序以及未来计划，并邀请全球研究人员为这一数据资源做出贡献。
