Sahoo Alaka, Jena Ajaya K, Kumar Paidesetty Sudhir, Panda Maitreyee
Prof. Maitreyee Panda, MBBS, MD Department of Skin and VD Institute of Medical Sciences & SUM Hospital, Siksha 'O' Anusandhan Deemed to be University Bhubenswar-751003 Odisha, India;
Acta Dermatovenerol Croat. 2024 Dec;32(4):173-180.
Oral lichen planus (OLP) is a chronic inflammatory and autoimmune condition of the oral mucosa with significant variation in pathophysiology. Accordingly, the present study aims to evaluate the socio-demographic profile of OLP patients in an eastern Indian population, examining the interplay between socio-economic status (SES), lifestyle factors, and disease characteristics.
This prospective study was conducted at a teaching hospital in eastern India from January 2019 to February 2022. Out of 1589 diagnosed OLP patients, 546 voluntarily agreed to participate in the study. We collected socio-demographic data, such as age, gender, education level, occupation, income, lifestyle habits, and comorbidity, through structured interviews and medical records. We performed statistical analyses using SPSS 20.0 software to identify significant associations between these variables and the clinical features of OLP.
Among the 546 participants, 54.02% were women and 45.97% were men, with the highest prevalence (40.10%) in the middle aged adult group (31-40 years). Furthermore, the majority of participants came from lower castes (64.64%), belonged to a lower socio-economic class (45.60%), and over 53% were involved in agricultural farming and daily labor. From a lifestyle perspective, 53.39% of participants were highly addicted to paan, gutka, cigarettes, and alcohol. Common comorbidities included hypertension (18.68%), diabetes (16.84%), thyroid disorders (10.62%), and past hepatitis C infection history (16.84%). Approximately 70.69% experienced stress, anxiety, and depression, while 21.79% frequently encountered chronic trauma post-OLP development.
This study highlights OLP prevalence and severity in a teaching hospital, where lower socio-economic status and lifestyle factors, such as tobacco use, comorbidities, and hepatitis C infection, are significantly associated with OLP manifestations.
口腔扁平苔藓（OLP）是一种口腔黏膜的慢性炎症性自身免疫性疾病，其病理生理学存在显著差异。因此，本研究旨在评估印度东部人群中OLP患者的社会人口学特征，研究社会经济地位（SES）、生活方式因素和疾病特征之间的相互作用。
本前瞻性研究于2019年1月至2022年2月在印度东部的一家教学医院进行。在1589例确诊的OLP患者中，546例自愿同意参与研究。我们通过结构化访谈和病历收集了社会人口学数据，如年龄、性别、教育水平、职业、收入、生活习惯和合并症。我们使用SPSS 20.0软件进行统计分析，以确定这些变量与OLP临床特征之间的显著关联。
在546名参与者中，54.02%为女性，45.97%为男性，中年成人组（31 - 40岁）患病率最高（40.10%）。此外，大多数参与者来自低种姓（64.64%），属于社会经济阶层较低（45.60%），超过53%从事农业种植和日常劳动。从生活方式角度看，53.39%的参与者对槟榔、古特卡、香烟和酒精高度上瘾。常见的合并症包括高血压（18.68%）、糖尿病（16.84%）、甲状腺疾病（10.62%）和既往丙型肝炎感染史（16.84%）。约70.69%的人经历过压力、焦虑和抑郁，而21.79%的人在OLP发病后经常遭遇慢性创伤。
本研究突出了一家教学医院中OLP的患病率和严重程度，其中社会经济地位较低以及吸烟、合并症和丙型肝炎感染等生活方式因素与OLP表现显著相关。
