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性别和年龄对实验大鼠血清醛固酮和甲状腺激素的影响。

Effect of sex and age on serum aldosterone and thyroid hormones in the laboratory rat.

作者信息

Tang F

出版信息

Horm Metab Res. 1985 Oct;17(10):507-9. doi: 10.1055/s-2007-1013590.

DOI:10.1055/s-2007-1013590
PMID:4065813
Abstract

Serum levels of aldosterone, tri-iodo thyronine (T3) and thyroxine (T4) were measured in male and female rats aged 3 months, 12 months, and 18 months. Female rats were found to have higher aldosterone and T3 levels, and lower T4 level than the male. No age-related change was observed in serum aldosterone in either sex. In contrast, serum T4 were found to decrease with age in both sexes while serum T3 showed an age-associated diminution in the male only. Serum testosterone was also measured in the male rats and was found to decline with age.

摘要

对3个月、12个月和18个月大的雄性和雌性大鼠的血清醛固酮、三碘甲状腺原氨酸(T3)和甲状腺素(T4)水平进行了测量。发现雌性大鼠的醛固酮和T3水平高于雄性,而T4水平低于雄性。在任何性别中,均未观察到血清醛固酮与年龄相关的变化。相比之下,发现两性的血清T4均随年龄下降,而血清T3仅在雄性中显示出与年龄相关的降低。还对雄性大鼠的血清睾酮进行了测量,发现其随年龄下降。

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Effect of sex and age on serum aldosterone and thyroid hormones in the laboratory rat.性别和年龄对实验大鼠血清醛固酮和甲状腺激素的影响。
Horm Metab Res. 1985 Oct;17(10):507-9. doi: 10.1055/s-2007-1013590.
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[Effect of 3,3',5' triiodo-L-Thyronine (rT3) on the serum concentration of thyroid hormones in rats].[3,3',5'-三碘-L-甲状腺原氨酸(反三碘甲状腺原氨酸,rT3)对大鼠血清甲状腺激素浓度的影响]
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J Endocrinol. 2007 Jan;192(1):121-30. doi: 10.1677/joe.1.06901.

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