Dhawan D, Sharma R, Sharma R R, Dash R J
Horm Metab Res. 1985 Feb;17(2):109-10. doi: 10.1055/s-2007-1013465.
Circulating thyroxine (T4) and triiodothyronine (T3) concentrations in rats were determined after various periods of lithium administration in diet. No significant change in serum T4 and T3 levels was observed after ten days of lithium treatment. However, lithium treatment for one month, two months and four months showed a significant decrease in serum T4 and T3 levels indicating the adverse effect of chronic lithium intake.
在给大鼠喂食不同时间段的锂后,测定了其循环甲状腺素(T4)和三碘甲状腺原氨酸(T3)的浓度。锂治疗十天后,血清T4和T3水平未观察到显著变化。然而,锂治疗一个月、两个月和四个月后,血清T4和T3水平显著降低,表明长期摄入锂具有不良影响。