Bacterial Heavy Metal Resistance in Contaminated Soil.

Soil heavy metal contamination poses a significant global threat to both environmental and human health. The accumulation of heavy metals in the Earth's crust, driven by urbanization, industrialization, agricultural practices, improper waste disposal, and mining, triggers harmful ecological cascades. Microorganisms, particularly bacteria, play a vital role in the decomposition and detoxification of these contaminants. In contaminated environments, bacteria exhibit resistance to heavy metals through various strategies, including the production of metal-chelating molecules, alterations to cell surface properties, efflux pumps, and activation of detoxification pathways. Notable microbial species such as , , , , and show promising potential for bioremediation efforts. Harnessing bacterial resistance to heavy metals offers a cost-effective and sustainable approach to mitigate the adverse impacts of contamination. This review explores the mechanisms of heavy metal resistance in bacteria, the role of soil microbiota, and the implications for bioremediation strategies. This review emphasizes the critical importance of bacterial resistance in addressing soil contamination and highlight the need for further research to elucidate underlying mechanisms and enhance bioremediation applications in this urgent global challenge.