Zhang Wancheng, Ruan Ye, Ling Jianglong
Longyan First Affiliated Hospital of Fujian Medical University, Longyan, 364000, China.
Institute of Labour Hygiene and Environmental Health, School of Public Health, Lanzhou University, Lanzhou, 730000, China.
Sci Rep. 2025 Jul 15;15(1):25466. doi: 10.1038/s41598-025-10532-x.
Research on the impact of changes in air pollutant concentrations during peak traffic hours on hospital admissions for respiratory diseases (RD) is limited. This study utilized a distributed lag nonlinear model (DLNM) to investigate this effect. Between 2014 and 2019, a total of 109,419 RD patients were hospitalized across seven hospitals in Lanzhou, China. Except for ozone (O), fine particulate matter (PM), inhalable particulate matter (PM), sulfur dioxide (SO), nitrogen dioxide (NO) and carbon monoxide (CO), which increased by 10 µg/m (1 mg/m for CO), the relative risk (RR) values of hospitalization for RD were 1.0211 [95% confidence interval (CI) 1.0090, 1.0333] (lag0-7), 1.0026 ( 95% CI 1.0010, 1.0043) (lag0), 1.0615 (95% CI 1.0355, 1.0882) (lag0-7), 1.0650 (95% CI 1.0478, 1.0824) (lag0-7) and 1.1229 (95% CI 1.0686, 1.1800) ( lag0-7), respectively. The stratified analyses revealed that air pollutants, except for O, affected both males and females. PM, PM, NO, and CO had a greater impact on individuals aged < 15 years, while SO had a more pronounced effect on those aged ≥ 65 years. The impact of air pollutants on RD hospitalizations was more significant during the cold season. It was recommended that people reduce short-term outdoor exposure during peak traffic hours.
关于交通高峰期空气污染物浓度变化对呼吸系统疾病(RD)住院人数的影响的研究有限。本研究利用分布滞后非线性模型(DLNM)来调查这种影响。2014年至2019年期间,中国兰州的七家医院共有109419名RD患者住院。除臭氧(O₃)、细颗粒物(PM₂.₅)、可吸入颗粒物(PM₁₀)、二氧化硫(SO₂)、二氧化氮(NO₂)和一氧化碳(CO)浓度每增加10 μg/m³(CO为1 mg/m³)外,RD住院的相对风险(RR)值分别为1.0211 [95%置信区间(CI)1.0090,1.0333](滞后0 - 7天)、1.0026(95% CI 1.0010,1.0043)(滞后0天)、1.0615(95% CI 1.0355,1.0882)(滞后0 - 7天)、1.0650(95% CI 1.0478,1.0824)(滞后0 - 7天)和1.1229(95% CI 1.0686,1.1800)(滞后0 - 7天)。分层分析显示,除O₃外,空气污染物对男性和女性均有影响。PM₂.₅、PM₁₀、NO₂和CO对15岁以下个体的影响更大,而SO₂对65岁及以上个体的影响更为明显。寒冷季节空气污染物对RD住院的影响更为显著。建议人们在交通高峰期减少短期户外暴露。