Chair and Department of Pneumonology, Oncology and Allergology, Medical University, Lublin, Poland.
Department of Pharmaceutical Botany, Medical University, Lublin, Poland.
Ann Agric Environ Med. 2024 Mar 25;31(1):13-23. doi: 10.26444/aaem/169486. Epub 2023 Jul 21.
Smog, which contains fine dusts, non-metal oxides, metals and organic compounds can have irritating, allergenic and immunomodulatory effects leading to the development of respiratory diseases and their exacerbations. The aim of the study was to search for a relationship between concentrations of air pollutants and the frequency of hospitalizations due to exacerbation of asthma, chronic obstructive pulmonary disease, or abnormalitis in breathing.
Hospital admission data was accessed from the hospital digital in-formation system. From the publicly available database of the Chief Inspectorate for Environmental Protection, data concerning the concentrations of pollutants, such as PM and PM, sulphur oxide IV (SO), nitric oxide IV (NO), carbon monoxide II (CO), benzene and ozone (O), measured daily with hourly accuracy was used. The results of the average concentrations of air pollutants were compared with the rates of hospitalization in the corresponding time intervals.
A number of statistically significant correlations were shown indicating the role of increased concentrations of each of the tested contaminants in the frequency of hospitalizations. In particular, strongly positive correlations were shown between the frequency of hospitalizations due to COPD and PM and PM, asthma with benzene and NO, and for respiratory disorders in general with benzene, CO and SO.
The results indicate that air pollution can be a significant modifiable risk factor for exacerbations of respiratory diseases and therefore its avoidance plays an important role in primary prevention.
雾霾含有细颗粒物、非金属氧化物、金属和有机化合物,可能具有刺激性、致敏性和免疫调节作用,导致呼吸道疾病及其恶化。本研究旨在寻找空气污染物浓度与因哮喘、慢性阻塞性肺疾病或呼吸异常而住院的频率之间的关系。
从医院数字信息系统获取住院数据。利用公共可用的环境保护总局数据库,每日每小时准确测量了污染物(如 PM 和 PM、二氧化硫 IV(SO)、二氧化氮 IV(NO)、一氧化碳 II(CO)、苯和臭氧(O))的浓度数据。将空气污染物的平均浓度结果与相应时间段内的住院率进行比较。
显示出一些具有统计学意义的相关性,表明测试污染物浓度的增加与住院频率之间存在关系。特别是,COPD 和 PM 与 PM、哮喘与苯和 NO 以及一般呼吸障碍与苯、CO 和 SO 之间存在强烈的正相关关系。
结果表明,空气污染可能是呼吸道疾病恶化的重要可改变风险因素,因此避免空气污染对于初级预防具有重要作用。