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本文引用的文献

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Fibrous foes: First report on insidious microplastic contamination in dietary fiber supplements.纤维之敌:膳食纤维补充剂中隐匿微塑料污染的首次报告。
Environ Pollut. 2024 Dec 15;363(Pt 2):125248. doi: 10.1016/j.envpol.2024.125248. Epub 2024 Nov 5.
2
DSHEA 1994 - Celebrating 30 Years of Dietary Supplement Regulation in the United States.1994年《膳食补充剂健康与教育法》——庆祝美国膳食补充剂监管30周年。
J Diet Suppl. 2025;22(1):1-8. doi: 10.1080/19390211.2024.2419434. Epub 2024 Oct 25.
3
Multivitamin Use and Mortality Risk in 3 Prospective US Cohorts.多维元素使用与 3 项美国前瞻性队列研究中的死亡率风险。
JAMA Netw Open. 2024 Jun 3;7(6):e2418729. doi: 10.1001/jamanetworkopen.2024.18729.
4
The Recommendation of the Mediterranean-styled Japanese Diet for Healthy Longevity.地中海式日本饮食有益于健康长寿的建议。
Endocr Metab Immune Disord Drug Targets. 2024;24(15):1794-1812. doi: 10.2174/0118715303280097240130072031.
5
The Regulatory Challenges of Placing Dietary Ingredients on the European and US Market.将膳食成分投放至欧洲和美国市场所面临的监管挑战。
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Nutrients. 2023 Dec 14;15(24):5113. doi: 10.3390/nu15245113.
8
Investigation of supplement use and knowledge among Japanese elite athletes for the Tokyo 2020 Olympic/Paralympic games and the Beijing 2022 winter Olympic/Paralympic games.对参加2020年东京奥运会/残奥会和2022年北京冬奥会/残奥会的日本精英运动员的补充剂使用情况及相关知识的调查。
Front Sports Act Living. 2023 Oct 18;5:1258542. doi: 10.3389/fspor.2023.1258542. eCollection 2023.
9
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Ann Allergy Asthma Immunol. 2023 Oct;131(4):412-420. doi: 10.1016/j.anai.2023.07.019. Epub 2023 Jul 28.
10
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关于膳食补充剂及该行业的常见问题与误解——科学和法律究竟是怎么说的?

"Common questions and misconceptions about dietary supplements and the industry - What does science and the law really say?".

作者信息

Antonio Jose, Antonio Brandi, Aragon Alan, Bustillo Erik, Candow Darren, Collins Rick, Davila Edwin, Durkin Bob, Kalman Douglas, Lockwood Chris, Mills Scotty, Stout Jeffrey R

机构信息

NSU Florida, Department of Health and Human Performance, College of Health Care Sciences, Davie, FL, USA.

University of Central Florida, School of Kinesiology and Rehabilitation Sciences, Orlando, Florida, USA.

出版信息

J Int Soc Sports Nutr. 2025 Dec;22(1):2534128. doi: 10.1080/15502783.2025.2534128. Epub 2025 Jul 15.

DOI:10.1080/15502783.2025.2534128
PMID:40662344
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12265102/
Abstract

Dietary supplement use is popular among fitness enthusiasts as well as competitive athletes. There is, however, confusion regarding the regulatory framework as well as the basic science regarding the use of supplements. Although there is an extensive body of scientific and legal writings on dietary supplements, several misconceptions persist vis-à-vis this category. Thus, the following questions will be addressed in this review. 1) Are dietary supplements regulated by the Food and Drug Administration? 2) Are foods and supplements regulated similarly? 3) What is the role of the Federal Trade Commission? 4) Besides federal regulations for dietary supplements, do state laws also regulate the category? 5) If a supplement company funds a study, does that automatically call into question the results? 6) Can diet alone provide everything you need without using supplements? 7) Is it necessary to conduct randomized controlled trials (RCTs) on dietary supplements? 8) How safe are supplements compared to OTC drugs? 9) Where can consumers find accurate information about supplements? 10) Why does the NIH fund dietary supplement research related to disease, yet findings cannot be marketed by supplement companies? 11) What is the size of the dietary supplement industry compared to the pharmaceutical industry? 12) How can I know if a dietary supplement is safe and free of banned substances? Similar to our prior papers, a team of legal and science scholars evaluated the evidence on these salient questions.

摘要

膳食补充剂的使用在健身爱好者以及竞技运动员中都很普遍。然而,对于膳食补充剂的监管框架以及其使用的基础科学存在困惑。尽管有大量关于膳食补充剂的科学和法律著作,但关于这一类别仍存在一些误解。因此,本综述将探讨以下问题。1)膳食补充剂是否受美国食品药品监督管理局监管?2)食品和补充剂的监管方式是否类似?3)联邦贸易委员会的作用是什么?4)除了联邦对膳食补充剂的规定外,州法律是否也对这一类别进行监管?5)如果一家补充剂公司资助一项研究,这是否会自动使研究结果受到质疑?6)仅靠饮食能否提供无需使用补充剂时所需的一切?7)是否有必要对膳食补充剂进行随机对照试验(RCT)?8)与非处方药相比,补充剂有多安全?9)消费者在哪里可以找到关于补充剂的准确信息?10)为什么美国国立卫生研究院资助与疾病相关的膳食补充剂研究,但研究结果却不能由补充剂公司进行营销?11)与制药行业相比,膳食补充剂行业的规模有多大?12)我如何知道一种膳食补充剂是否安全且不含违禁物质?与我们之前的论文类似,一组法律和科学学者评估了这些关键问题的证据。