Philmus Benjamin, Avalon Nicole E, Ding Yousong, Doering Drew T, Eustáquio Alessandra S, Gerwick William H, Luesch Hendrik, Orjala Jimmy, Sutherland Shaz, Taton Arnaud, Udwary Daniel
Department of Pharmaceutical Sciences, Oregon State University, Corvallis, OR, 97333, USA.
Department of Pharmaceutical Sciences, School of Pharmacy & Pharmaceutical Sciences, University of California, Irvine, Irvine, CA, 92617, USA.
Nat Prod Rep. 2025 Jul 15. doi: 10.1039/d5np00016e.
Cyanobacteria are prolific producers of biologically active compounds that are important in influencing ecology, behavior of interacting organisms, and as leads in drug discovery efforts. Here we discuss the challenges faced by all natural product researchers, especially those that focus on cyanobacteria, and then describe progress that has been made in these areas. We also propose some solutions, paths forward, and thoughts for consideration on these challenges.
蓝细菌是生物活性化合物的丰富生产者，这些化合物对于影响生态、相互作用生物的行为以及在药物发现工作中作为先导具有重要意义。在此，我们讨论所有天然产物研究人员所面临的挑战，尤其是那些专注于蓝细菌的研究人员，然后描述在这些领域所取得的进展。我们还针对这些挑战提出了一些解决方案、前进方向以及供思考的想法。
