Sun Yanwu, Chen Zhiping, Tang Zihan, Xu Zhenyu, Pan Hongfeng, Chi Pan, Huang Ying
Department of Colorectal Surgery, Fujian Medical University, Union Hospital, 29 Xinquan Road, Fuzhou, 350001, Fujian, People's Republic of China.
Discov Oncol. 2025 Jul 16;16(1):1347. doi: 10.1007/s12672-025-03034-9.
Our study aimed to perform a comprehensive bibliometric analysis to investigate the evolution of research in locally advanced colon cancer (LACC) over the past 30 years. This study examined 206 articles from the Science Citation Index Expanded within the Web of Science database, spanning from 1991 to 2023. It encompassed a detailed review of publication trends, geographic distribution, institutional contributions, authorship patterns, and keyword analysis. Publications in LACC research saw a substantial increase in publications starting in 2016, with China emerging as the primary contributor, followed by the USA and Japan. Our analysis revealed a shift in research focus from traditional management to advanced treatment approaches, including neoadjuvant therapy and complete mesocolic excision. Keywords, such as "carcinomatosis", "systemic chemotherapy", and "cytoreductive surgery" have become prominent, reflecting evolving research hotspots. However, the low centrality among top authors indicates a preference for independent research over collaborative efforts. This bibliometric study highlights significant advancements and shifts in LACC research over the last 30 years, highlighting an increasing focus on advanced therapeutic approaches. Enhancing international collaboration is essential to enhance LACC research, potentially improving treatments and patient outcomes. Our study provides a foundational reference for guiding future research and fostering collaborative efforts in the field.
我们的研究旨在进行全面的文献计量分析，以调查过去30年局部晚期结肠癌（LACC）研究的演变。本研究审查了科学网数据库中《科学引文索引扩展版》的206篇文章，时间跨度为1991年至2023年。它包括对出版趋势、地理分布、机构贡献、作者模式和关键词分析的详细回顾。LACC研究的出版物从2016年开始大幅增加，中国成为主要贡献者，其次是美国和日本。我们的分析表明，研究重点从传统管理转向了先进的治疗方法，包括新辅助治疗和完整结肠系膜切除术。“癌病”、“全身化疗”和“细胞减灭术”等关键词变得突出，反映了不断演变的研究热点。然而，顶级作者之间的低中心性表明，相较于合作研究，更倾向于独立研究。这项文献计量研究突出了过去30年LACC研究的重大进展和转变，强调了对先进治疗方法的日益关注。加强国际合作对于加强LACC研究至关重要，这可能会改善治疗方法和患者预后。我们的研究为指导该领域未来的研究和促进合作努力提供了基础参考。
