Whitehead F, Jarvis L R, Skinner J M, Whitehead R
J Clin Pathol. 1985 Nov;38(11):1261-4. doi: 10.1136/jcp.38.11.1261.
The nuclei of colonic adenomatous polyps and some colonic carcinomas have a normal diploid profile. The remaining carcinomas are aneuploid, and this change most probably occurs after the dysplasia that determines invasiveness, because even adenomatous polyps with carcinoma in situ are diploid.
结肠腺瘤性息肉和一些结肠癌的细胞核具有正常的二倍体特征。其余的癌是非整倍体,这种变化很可能发生在决定侵袭性的发育异常之后,因为即使是原位癌的腺瘤性息肉也是二倍体。