Gemme Élodie, Lagacé-Wiens Philippe, Keynan Yoav, Wuerz Terry, McEachern James, Embil John M
Department of Medical Microbiology and Infectious Diseases, Max Rady College of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
Clinical Microbiology, Diagnostic Services, Shared Health, Winnipeg, Manitoba, Canada.
J Assoc Med Microbiol Infect Dis Can. 2025 Jan 31;10(1):84-89. doi: 10.3138/jammi-2024-0031. eCollection 2025 Mar.
Tularemia is a zoonotic disease of the Northern Hemisphere caused by . Given its diverse animal reservoir and wide range of transmission modes, a thorough history of potential exposure is paramount. In the right context, fever combined with skin eruption and lymphadenopathy should raise the possibility of tularemia. Additionally, health care providers should be mindful that is a risk group 3 pathogen and a category A bioterrorism agent and presents a risk for laboratory personnel due to its aerosolization potential, low infectious dose, and fatality rate ranging from 2% to 60%.
Retrospective single chart review.
We describe a 65-year-old man with tularemia working as a bear-hunting guide whose management was delayed despite a fairly typical presentation due to lack of awareness regarding this disease. This case also demonstrates the need for safer referral practices and improved communications with the laboratory to ensure personnel are taking the appropriate measures while handling patient samples to avoid potentially serious consequences.
The diagnosis was confirmed from a neck mass biopsy and the patient made a complete recovery with appropriate antibiotic treatment.
兔热病是一种发生在北半球的人畜共患病,由……引起。鉴于其多样的动物宿主和广泛的传播方式,全面了解潜在暴露史至关重要。在恰当的情况下,发热伴皮疹和淋巴结病应提高兔热病的可能性。此外,医疗保健人员应注意,……是3类风险病原体和A类生物恐怖主义制剂,因其具有形成气溶胶的可能性、低感染剂量以及2%至60%的病死率,对实验室人员构成风险。
回顾性单病例病历审查。
我们描述了一名65岁患兔热病的男子,他是一名猎熊向导,尽管临床表现相当典型,但由于对该病认识不足,其治疗被延误。该病例还表明需要更安全的转诊做法,并改善与实验室的沟通,以确保人员在处理患者样本时采取适当措施,避免潜在的严重后果。
通过颈部肿块活检确诊,患者经适当的抗生素治疗后完全康复。