Demers R Y, Demers P, Hoar S K, Deighton K
J Occup Med. 1985 Nov;27(11):809-12. doi: 10.1097/00043764-198511000-00012.
A group of 902 pattern and model makers were screened for colorectal cancer and polyps using a 60-cm flexible sigmoidoscope. Three recent mortality studies have found a significant excess of colorectal malignant neoplasms in this occupational group. Four adenocarcinomas, two carcinoids, and two cancers in situ were found. In addition, 150 (17%) of the individuals were found to have polyps. Among white males 40 to 70 years of age, the prevalence rate was found to be 23%. The prevalence of colorectal polyps among the pattern and model makers was compared with that of four previously studied asymptomatic populations who were also examined using a 60-cm flexible sigmoidoscope. Polyp rates were found to be significantly greater among pattern and model makers than among three of the four comparison populations. The odds ratios between these three populations and the study population ranged from 1.9 to 2.7 and closely approximate the ratios found in previous studies evaluating colon cancer in this occupational group.
使用60厘米的可弯曲乙状结肠镜对902名模具工进行了结肠直肠癌和息肉筛查。最近的三项死亡率研究发现，这个职业群体中的结肠恶性肿瘤显著过多。发现了4例腺癌、2例类癌和2例原位癌。此外，发现150名（17%）个体有息肉。在40至70岁的白人男性中，患病率为23%。将模具工中结肠息肉的患病率与之前使用60厘米可弯曲乙状结肠镜检查的四个无症状人群的患病率进行了比较。发现模具工中的息肉发生率明显高于四个对照人群中的三个。这三个人群与研究人群之间的优势比在1.9至2.7之间，与之前评估这个职业群体结肠癌的研究中发现的比率非常接近。
