诊断历程：表现为快速进展性痴呆的原发性中枢神经系统淋巴瘤（脑淋巴瘤）
Diagnostic Odyssey: Primary CNS Lymphoma (Lymphoma Cerebri) Presenting as Rapidly Progressive Dementia.
作者信息
Lei Yuanli, Asharf Aqsa, Amos Jessica, Khawandanah Mohamad, Annan Anand, Battiste James, Torbey Michel, Al-Juhaishi Taha, Anadani Nidhiben
机构信息
Department of Medicine, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.
Section of Hematology-Oncology, Department of Medicine, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.
出版信息
Case Rep Hematol. 2025 Jul 9;2025:8819799. doi: 10.1155/crh/8819799. eCollection 2025.
Primary central nervous system lymphoma (PCNSL) is a rare brain cancer that sometimes presented as rapidly progressive dementia. Diagnosing PCNSL presenting with rapidly progressive neurocognitive symptoms can be challenging, especially when the patient was previously treated with immunosuppressants for suspected autoimmune processes. We present a case where PCNLS was eventually and successfully treated 18 months after neurological symptoms started.
原发性中枢神经系统淋巴瘤（PCNSL）是一种罕见的脑癌，有时表现为快速进展性痴呆。诊断表现为快速进展性神经认知症状的PCNSL可能具有挑战性，尤其是当患者先前因疑似自身免疫性疾病而接受免疫抑制剂治疗时。我们报告一例病例，该患者在出现神经症状18个月后最终成功治愈了PCNLS。
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