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前列腺癌根治术后自我报告的恢复质量——一项前瞻性队列研究。

Self-reported quality of recovery after radical prostatectomy-a prospective cohort study.

作者信息

Fischer Marlene, Küllmei Josephine, Krause Linda, Wei Peipei, Kahl Ursula, Kainz Elena, Mewes Caspar, Graefen Markus, Haese Alexander, Zöllner Christian, Plümer Lili

机构信息

Department of Anesthesiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Department of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.

出版信息

Qual Life Res. 2025 Jul 18. doi: 10.1007/s11136-025-04026-6.

Abstract

PURPOSE

The Quality of Recovery-15 questionnaire (QoR-15) has been developed to assess patient-reported recovery 24 h after non-cardiac surgery. This prospective cohort study sought to analyze patient-reported recovery throughout day five after open radical retropubic prostatectomy (ORP) and robot-assisted radical retropubic prostatectomy (RARP).

METHODS

Between June 2022 and February 2023 adult patients, who were scheduled for elective radical prostatectomy, completed the German version of the QoR-15 (QoR-15GE) preoperatively to establish a baseline value. Between postoperative day one and day five, patients completed the QoR-15GE daily until the day of discharge.

RESULTS

A total of 523 patients completed the questionnaires. On postoperative day one QoR-15GE scores were significantly lower after RARP compared with ORP (ORP: 113 ± 22 vs. RARP: 107 ± 24; p = 0.006) with a higher decline in postoperative QoR-15GE scores in RARP compared with ORP patients (ORP: 27 ± 20 vs. RARP: 32 ± 23; p = 0.006). The multivariable analysis confirmed an influence of surgical technique (Estimate: 4.39; 95% CI [0.27; 8.50], p = 0.037) on postoperative quality of recovery after adjusting for clinically relevant variables. Irrespective of surgical technique, we observed a consistent increase in QoR-15GE scores with similar recovery scores on postoperative days three, four, and five.

CONCLUSION

Patients who undergo RARP experience poorer postoperative recovery at postoperative days one and two compared to those undergoing ORP. However, recovery scores align from postoperative day three, indicating a similar level of patient-reported recovery before hospital discharge. These findings suggest that the QoR-15GE may be appropriate for serial assessments.

摘要

目的

恢复质量-15问卷(QoR-15)已被开发用于评估非心脏手术后24小时患者报告的恢复情况。这项前瞻性队列研究旨在分析开放性耻骨后根治性前列腺切除术(ORP)和机器人辅助耻骨后根治性前列腺切除术(RARP)后第5天全天患者报告的恢复情况。

方法

在2022年6月至2023年2月期间,计划进行择期根治性前列腺切除术的成年患者在术前完成德文版的QoR-15(QoR-15GE)以建立基线值。在术后第1天至第5天,患者每天完成QoR-15GE,直至出院。

结果

共有523名患者完成了问卷调查。术后第1天,RARP术后的QoR-15GE评分显著低于ORP术后(ORP:113±22 vs. RARP:107±24;p = 0.006),与ORP患者相比,RARP患者术后QoR-15GE评分下降幅度更大(ORP:27±20 vs. RARP:32±23;p = 0.006)。多变量分析证实,在调整临床相关变量后,手术技术对术后恢复质量有影响(估计值:4.39;95%可信区间[0.27;8.50],p = 0.037)。无论手术技术如何,我们观察到术后第3天、第4天和第5天QoR- ISGE评分持续增加,恢复评分相似。

结论

与接受ORP的患者相比,接受RARP的患者在术后第1天和第2天的术后恢复较差。然而,从术后第3天开始恢复评分趋于一致,表明出院前患者报告的恢复水平相似。这些发现表明,QoR-15GE可能适用于连续评估。

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