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大麻使用与遵守新冠疫情公共卫生指南之间的关联:来自法国CONSTANCES队列和SAPRIS调查的前瞻性分析

The association between cannabis use and adherence to COVID-19 public health guidelines: prospective analyses from the French CONSTANCES cohort and SAPRIS survey.

作者信息

Haddad Rita El, Wiernik Emmanuel, Kab Sofiane, Zins Marie, Airagnes Guillaume

机构信息

Université Paris Cité, Paris Saclay University, Université de Versailles Saint- Quentin-en-Yvelines, INSERM UMS 011 « Population-based Cohorts Unit », Paris, France.

Université Paris Cité, Paris Saclay University, Université de Versailles Saint-Quentin-en-Yvelines, INSERM UMS 011 « Population- based Cohorts Unit », 16 Avenue Paul Vaillant-Couturier, Villejuif Cedex, 94897, France.

出版信息

Harm Reduct J. 2025 Jul 18;22(1):121. doi: 10.1186/s12954-025-01278-w.

DOI:10.1186/s12954-025-01278-w
PMID:40682147
Abstract

OBJECTIVE

To examine the association between the frequency of cannabis use and adherence to COVID-19 public health guidelines among adults in France between April and October 2020.

METHODS

Data from the CONSTANCES cohort on 39,450 adults participating in the SAPRIS survey were analyzed. The associations between non-adherence to handwashing, mask-wearing and social distancing and cannabis use frequency in 2019 at two periods of time, wave 1 + 2 (confinement) and wave 3 (deconfinement), were examined using binary logistic regression. The models were adjusted for age, sex, education, marital status, accommodation, tobacco use, self-rated health, anxiety and depressive symptoms.

RESULTS

Compared to no cannabis use during the past 12 months, cannabis use less than once per month was negatively associated with handwashing at wave 3 (Odds Ratio [95% Confidence Interval]) 1.46 [1.28-1.66], mask-wearing at wave 1 + 2 (1.26 [1.05-1.52]) and at wave 3 (1.60 [1.35-1.89]) and social distancing at wave 1 + 2 (1.32 [1.16-1.50]) and at wave 3 (1.55[1.32-1.83]). Cannabis use once per month or more was negatively associated with mask-wearing at wave 3 (1.41 [1.11-1.80]) and social distancing at wave 1 + 2 (1.27 [1.06-1.52]) and at wave 3 (1.57 [1.25-1.98]).

CONCLUSION

Cannabis use may be associated with less adherence to COVID-19 public health guidelines.

摘要

目的

研究2020年4月至10月期间法国成年人中大麻使用频率与遵守新冠疫情公共卫生指南之间的关联。

方法

对CONSTANCES队列中参与SAPRIS调查的39450名成年人的数据进行分析。使用二元逻辑回归分析了在两个时间段,即第1 + 2波(封锁期)和第3波(解封期),2019年不遵守洗手、佩戴口罩和保持社交距离与大麻使用频率之间的关联。模型对年龄、性别、教育程度、婚姻状况、居住条件、烟草使用、自评健康状况、焦虑和抑郁症状进行了调整。

结果

与过去12个月未使用大麻相比,每月使用大麻少于一次与第3波时的洗手(优势比[95%置信区间])1.46 [1.28 - 1.66]、第1 + 2波时的佩戴口罩(1.26 [1.05 - 1.52])和第3波时的佩戴口罩(1.60 [1.35 - 1.89])以及第1 + 2波时的保持社交距离(1.32 [1.16 - 1.50])和第3波时的保持社交距离(1.55[1.32 - 1.83])呈负相关。每月使用大麻一次或以上与第3波时的佩戴口罩(1.41 [1.11 - 1.80])以及第1 + 2波时的保持社交距离(1.27 [1.06 - 1.52])和第3波时的保持社交距离(1.57 [1.25 - 1.98])呈负相关。

结论

大麻使用可能与较少遵守新冠疫情公共卫生指南有关。

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