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胃肠道间质瘤的CT检查

CT of gastrointestinal stromal tumor.

作者信息

Ahmed Taha M, Fishman Elliot K

机构信息

Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 601 N Caroline St, Baltimore, MD 21287, USA.

出版信息

Radiol Case Rep. 2025 Jul 7;20(9):4825-4828. doi: 10.1016/j.radcr.2025.05.098. eCollection 2025 Sep.

DOI:10.1016/j.radcr.2025.05.098
PMID:40686801
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12273414/
Abstract

Gastrointestinal stromal tumors (GISTs), the most common sarcoma of the gastrointestinal tract, are mesenchymal tumors that generally arise in adults with a peak incidence in the sixth decade of life. Though most frequently found in the stomach or small intestine, GISTs may develop anywhere along the gastrointestinal tract. Approximately 1 in 4 GISTs are diagnosed incidentally, with imaging playing a crucial role in their detection and characterization. Due to their often clinically insidious growth, up to 25% of patients may already have metastatic disease at the time of diagnosis. In this article, we report the case of a 67-year-old woman who was incidentally diagnosed with a duodenal GIST. We analyze the computed tomography imaging findings and correlate them with the patient's clinical features.

摘要

胃肠道间质瘤(GISTs)是胃肠道最常见的肉瘤,是一种间叶组织肿瘤,通常发生于成年人,发病高峰在60岁左右。虽然GISTs最常出现在胃或小肠,但也可能在胃肠道的任何部位发生。约四分之一的GISTs是偶然诊断出来的,影像学在其检测和特征描述中起着关键作用。由于其生长往往在临床上较为隐匿,高达25%的患者在诊断时可能已经发生转移。在本文中,我们报告了一例67岁女性偶然诊断为十二指肠GIST的病例。我们分析了计算机断层扫描成像结果,并将其与患者的临床特征相关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f723/12273414/b776bd9b2e80/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f723/12273414/b776bd9b2e80/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f723/12273414/b776bd9b2e80/gr1.jpg

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本文引用的文献

1
Gastrointestinal Stromal Tumors (GIST): A Population-Based Study Using the SEER Database, including Management and Recent Advances in Targeted Therapy.胃肠道间质瘤(GIST):一项基于监测、流行病学和最终结果(SEER)数据库的人群研究,包括管理及靶向治疗的最新进展
Cancers (Basel). 2022 Jul 28;14(15):3689. doi: 10.3390/cancers14153689.
2
Characteristics of Gastrointestinal Stromal Tumors incidentally discovered during abdominal surgery.腹部手术中偶然发现的胃肠道间质瘤的特征
Am J Surg. 2021 Nov;222(5):983-988. doi: 10.1016/j.amjsurg.2021.04.010. Epub 2021 Apr 22.
3
Clinical Presentation of Gastrointestinal Stromal Tumors.
胃肠道间质瘤的临床表现
Visc Med. 2018 Oct;34(5):335-340. doi: 10.1159/000494303. Epub 2018 Oct 13.
4
Gastrointestinal Stromal Tumors.胃肠道间质瘤。
J Clin Oncol. 2018 Jan 10;36(2):136-143. doi: 10.1200/JCO.2017.74.9705. Epub 2017 Dec 8.
5
Classification of gastrointestinal stromal tumor syndromes.胃肠道间质瘤综合征的分类。
Endocr Relat Cancer. 2018 Feb;25(2):R49-R58. doi: 10.1530/ERC-17-0329. Epub 2017 Nov 23.
6
"Wild type" GIST: Clinicopathological features and clinical practice.“野生型”胃肠道间质瘤:临床病理特征与临床实践
Pathol Int. 2016 Aug;66(8):431-7. doi: 10.1111/pin.12431. Epub 2016 Jul 18.
7
Asian Consensus Guidelines for the Diagnosis and Management of Gastrointestinal Stromal Tumor.亚洲胃肠间质瘤诊断与管理共识指南。
Cancer Res Treat. 2016 Oct;48(4):1155-1166. doi: 10.4143/crt.2016.187. Epub 2016 Jun 24.
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Follow-up strategies for patients with gastrointestinal stromal tumour treated with or without adjuvant imatinib after surgery.胃肠道间质瘤患者术后接受或未接受伊马替尼辅助治疗的随访策略。
Eur J Cancer. 2015 Aug;51(12):1611-7. doi: 10.1016/j.ejca.2015.05.009. Epub 2015 May 25.
9
Gastrointestinal stromal tumour.胃肠道间质瘤。
Lancet. 2013 Sep 14;382(9896):973-83. doi: 10.1016/S0140-6736(13)60106-3. Epub 2013 Apr 24.
10
Pathology of gastrointestinal stromal tumors.胃肠道间质瘤的病理学
Clin Med Insights Pathol. 2012;5:23-33. doi: 10.4137/CPath.S9689. Epub 2012 Jul 17.