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靶向CD45的正电子发射断层扫描(PET)能够实现炎症状态的可视化。

CD45-targeted PET enables the visualization of inflammatory conditions.

作者信息

Li Chongjiao, Song Zhendong, Hu Qilong, Li Yinlong, Patel Jimmy S, Liang Steven H

机构信息

Department of Radiology and Imaging Sciences, Emory University Atlanta, Georgia 30322, USA.

出版信息

Am J Nucl Med Mol Imaging. 2025 Jun 25;15(3):124-129. doi: 10.62347/VFWR2835. eCollection 2025.

Abstract

Inflammation is a major contributor to human mortality, accounting for over 50% of deaths worldwide. Therefore, there is an urgent need for early and accurate diagnostic methods. PET imaging targeting leukocyte common antigen CD45 presents a promising approach for detecting inflammation and monitoring therapeutic responses.

摘要

炎症是导致人类死亡的主要因素,全球超过50%的死亡病例与之相关。因此,迫切需要早期准确的诊断方法。靶向白细胞共同抗原CD45的正电子发射断层扫描(PET)成像为检测炎症和监测治疗反应提供了一种很有前景的方法。

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