Paleri Varsha Aravind, Hens Kristien
Centre for Ethics, Department of Philosophy, Universiteit Antwerpen, Stadscampus, 2000, Antwerpen, Belgium.
Synth Syst Biotechnol. 2025 Jun 23;10(4):1180-1189. doi: 10.1016/j.synbio.2025.06.006. eCollection 2025 Dec.
Synthetic Biology (SynBio) is an interdisciplinary field that tackles global challenges in healthcare, sustainability, food production, among others. However, it also presents critical ethical concerns, including biosecurity, justice, and the unintended consequences of research biases. Addressing these concerns requires timely and systematic ethical evaluation. Conventional approaches often relegate ethics to an external, procedural role rather than embedding it within the core of scientific inquiry, leading to delayed engagement and associated challenges. This article introduces a structured, stage-wise Standard Operating Procedure (SOP) to support the systematic integration of ethics into scientific research. Particularly beneficial for early-career researchers and ethicists, this framework offers a practical method for incorporating ethical reflection throughout the research process.
合成生物学（SynBio）是一个跨学科领域，致力于应对医疗保健、可持续发展、粮食生产等方面的全球挑战。然而，它也引发了关键的伦理问题，包括生物安全、公正以及研究偏差的意外后果。解决这些问题需要及时且系统的伦理评估。传统方法往往将伦理置于外部的程序角色，而非将其融入科学探究的核心，导致参与延迟及相关挑战。本文介绍一种结构化、分阶段的标准操作规程（SOP），以支持将伦理系统地融入科学研究。该框架对早期职业研究人员和伦理学家特别有益，提供了一种在整个研究过程中纳入伦理思考的实用方法。
