Cleve H
Naturwissenschaften. 1985 Oct;72(10):519-26. doi: 10.1007/BF00367597.
The vitamin-D-binding protein (DBP) also known as group-specific component (GC) is described. This transport protein for vitamin D and its metabolic derivatives has genetic variants which are disclosed by electrophoretic procedures or by isoelectric focusing. Three common and one hundred rare alleles are known. The biochemical, molecular and population genetics are briefly outlined as an example of inherited variability in man.
本文描述了维生素D结合蛋白(DBP),也称为组特异性成分(GC)。这种维生素D及其代谢衍生物的转运蛋白具有遗传变异,可通过电泳程序或等电聚焦来揭示。已知有三种常见等位基因和一百种罕见等位基因。作为人类遗传变异性的一个例子,简要概述了其生化、分子和群体遗传学。