Liu Cuijuan, Ma Jing, Wang Pengfen, Liu Wei, Zhang Miaomiao
Department of Ophthalmology, The Second People's Hospital of Jinan, 148# Jingyi Road, Jinan, 250001, People's Republic of China.
Int Ophthalmol. 2025 Jul 22;45(1):308. doi: 10.1007/s10792-025-03689-x.
To assess sleep quality of glaucoma patients using cardiopulmonary coupled CPC monitoring.
276 patients from July 2021 to May 2022 were continuously collected. 176 patients including 95 patients with acute angle-closure glaucoma (group A) and 81 patients with chronic angle-closure glaucoma (group B) were enrolled, 100 cataract patients (group C) as the control group. The CPC monitoring was performed on the enrolled patients. According to diseases types and CPC results, the sleep quality of the glaucoma patients was analyzed.
The total sleep time (TST) of group A was 6.91 ± 1.471 h, while Group B's TST was 7.14 ± 0.637 h. Group C's TST was 7.45 ± 0.852 h. The sleep efficiency (TIB) of group A was 80.128 ± 10.959, and group B's TIB was 80.246 ± 9.936. Group C's TIB was 85.451 ± 6.534. The Apnea-Hypopnea Index (AHI) of group A was 17.923 ± 19.901, and group B's AHI was 15.438 ± 15.818. Group C's AHI was 9.481 ± 10.494. The difference between the group A and group B was statistically significant, and the differences among the group A, B and the group C was statistically significant in the three sets of data.
PACG patients, especially with acute presentation (PAACG), demonstrate significantly disrupted sleep and higher AHI versus controls via CPC monitoring. These findings advocate for embedding sleep-disordered breathing screening into routine glaucoma management using CPC as a practical triage tool.
使用心肺耦合(CPC)监测评估青光眼患者的睡眠质量。
连续收集2021年7月至2022年5月的276例患者。纳入176例患者,其中包括95例急性闭角型青光眼患者(A组)和81例慢性闭角型青光眼患者(B组),100例白内障患者(C组)作为对照组。对纳入的患者进行CPC监测。根据疾病类型和CPC结果,分析青光眼患者的睡眠质量。
A组的总睡眠时间(TST)为6.91±1.471小时,而B组的TST为7.14±0.637小时。C组的TST为7.45±0.852小时。A组的睡眠效率(TIB)为80.128±10.959,B组的TIB为80.246±9.936。C组的TIB为85.451±6.534。A组的呼吸暂停低通气指数(AHI)为17.923±19.901,B组的AHI为15.438±15.818。C组的AHI为9.481±10.494。A组和B组之间的差异具有统计学意义,A组、B组和C组之间的差异在三组数据中均具有统计学意义。
通过CPC监测,原发性急性闭角型青光眼(PACG)患者,尤其是急性发作型(PAACG)患者,与对照组相比,睡眠明显紊乱,AHI更高。这些发现主张将睡眠呼吸障碍筛查纳入常规青光眼管理,使用CPC作为一种实用的分诊工具。