Wang Lu, Su Xin-Tong, Cao Yan, Yang Na-Na, Hao Xiao-Wan, Li Hong-Ping, Wang Qing-Yong, Yang Jing-Wen
School of Acupuncture-Moxibustion and Tuina, International Acupuncture and Moxibustion Innovation Institute, Beijing University of Chinese Medicine, Beijing, China.
Front Neurol. 2022 Oct 28;13:1030747. doi: 10.3389/fneur.2022.1030747. eCollection 2022.
Ischemic stroke is the predominant cause of long-term disability and death worldwide. It is attributable to the sudden interruption of regional cerebral blood flow, resulting in brain cell death and neurological impairment. Acupuncture is a widely used adjuvant treatment for ischemic stroke in China and shows promising efficacy in clinical practice. This review mainly focused on the evidence to illustrate several possible mechanisms of acupuncture therapy on cerebral perfusion in ischemic stroke. Studies have shown that acupuncture is probably effective in the enhancement of cerebral perfusion after ischemic stroke. It promotes the improvement of hemodynamics, the release of vasoactive substances, the formation of new blood vessels, as well as the restitution of microcirculation. Multiple factors may contribute to the variability in acupuncture's therapeutic effects, including the acupoint selection, stimulation frequency and intensity, and retaining needle time. Acupuncture has the potential to become a non-pharmacological adjuvant approach to enhance cerebral perfusion in ischemic stroke. Future studies are required to gain our insight into acupuncture as well as accelerate its clinical translation.
缺血性中风是全球长期残疾和死亡的主要原因。它是由于局部脑血流突然中断，导致脑细胞死亡和神经功能障碍。在中国，针灸是一种广泛用于缺血性中风的辅助治疗方法，在临床实践中显示出有前景的疗效。本综述主要聚焦于相关证据，以阐明针刺疗法对缺血性中风脑灌注的几种可能机制。研究表明，针灸可能对缺血性中风后增强脑灌注有效。它促进血流动力学的改善、血管活性物质的释放、新血管的形成以及微循环的恢复。多种因素可能导致针灸治疗效果的差异，包括穴位选择、刺激频率和强度以及留针时间。针灸有潜力成为一种增强缺血性中风脑灌注的非药物辅助方法。未来需要开展研究以深入了解针灸，并加速其临床转化。
